Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: methylbutenol synthase

Species: Pinus sabiniana

Summary:
An enzyme preparation from pine needles of Pinus sabiniana was partially purified and characterized for its biochemical properties. The enzyme catalyzes the conversion of dimethylallyl diphosphate to methylbutenol via the methylerythritol phosphate pathway I. This enzyme is distinct from the analogous linalool synthase, as it carries no specificity for geranyl diphosphate [Fisher00]. The enzyme requires Mn2+ for activity.

Gene-Reaction Schematic: ?

Credits:
Created 26-Sep-2011 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: methylbutenol synthase

dimethylallyl diphosphate + H2O <=> methylbutenol + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Reversibility of this reaction is unspecified.

In Pathways: methylbutenol biosynthesis

Kinetic Parameters:

Substrate
Km (μM)
Citations
dimethylallyl diphosphate
4.8
[Fisher00]

pH(opt): 7.5 [Fisher00]


References

Fisher00: Fisher AJ, Baker BM, Greenberg JP, Fall R (2000). "Enzymatic synthesis of methylbutenol from dimethylallyl diphosphate in needles of Pinus sabiniana." Arch Biochem Biophys 383(1);128-34. PMID: 11097185


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC14B.