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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
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MetaCyc Enzyme: peroxisomal choline monooxygenase

Gene: CMO Accession Number: G-14627 (MetaCyc)

Species: Hordeum vulgare

Summary:
A cDNA clone was isolated from Hordeum vulgare seedlings. The youngest leaves of seedlings were treated to abiotic stress and used for RNA extraction. The cDNA encoded a gene that shared identity with choline monooxygenases (CMO) of higher plants. Subcellular fractionation showed that the barley CMO was localized to peroxisomes. The expression analysis indicated more abundance in leaves, unlike betaine aldehyde dehydrogenase which was more abundant in awns and florets. Choline oxidation in GB synthesis is mediated by a peroxisomal NADPH-dependent choline monooxygenase in barley [Mitsuya11].

Molecular Weight of Polypeptide: 44.7 kD (from nucleotide sequence)

Unification Links: Entrez-Nucleotide:AB434467 , Entrez:BAG74777 , Protein Model Portal:B5UAE1 , UniProt:B5UAE1

Relationship Links: InterPro:IN-FAMILY:IPR001663 , InterPro:IN-FAMILY:IPR015879 , InterPro:IN-FAMILY:IPR017941 , Pfam:IN-FAMILY:PF00355 , Pfam:IN-FAMILY:PF00848 , Prints:IN-FAMILY:PR00090 , Prosite:IN-FAMILY:PS51296

Gene-Reaction Schematic: ?

Credits:
Created 17-Aug-2011 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: choline monooxygenase

EC Number: 1.1.1.-

choline + NADP+ <=> betaine aldehyde + NADPH + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Reversibility of this reaction is unspecified.


Enzymatic reaction of: choline monooxygenase

EC Number: 1.1.99.1

choline + an oxidized electron acceptor <=> betaine aldehyde + a reduced electron acceptor

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

This reaction is reversible.

In Pathways: choline degradation I


References

Mitsuya11: Mitsuya S, Kuwahara J, Ozaki K, Saeki E, Fujiwara T, Takabe T (2011). "Isolation and characterization of a novel peroxisomal choline monooxygenase in barley." Planta. PMID: 21769646


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC13B.