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MetaCyc Enzyme: malonyl-ACP synthetase

Species: Pisum sativum

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Credits:
Created 26-Apr-2011 by Zhang P , TAIR


Enzymatic reaction of: malonyl-ACP synthetase

EC Number: 6.2.1.-

malonate + a holo-[acyl-carrier protein] + ATP <=> a malonyl-[acp] + AMP + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: fatty acid biosynthesis (plant mitochondria)

Kinetic Parameters:

Substrate
Km (μM)
Citations
a holo-[acyl-carrier protein]
53.0
[Gueguen00]
malonate
50.0
[Gueguen00]


References

Byers07: Byers DM, Gong H (2007). "Acyl carrier protein: structure-function relationships in a conserved multifunctional protein family." Biochem Cell Biol 85(6);649-62. PMID: 18059524

Gueguen00: Gueguen V, Macherel D, Jaquinod M, Douce R, Bourguignon J (2000). "Fatty acid and lipoic acid biosynthesis in higher plant mitochondria." J Biol Chem 275(7);5016-25. PMID: 10671542


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Jul 7, 2015, biocyc11.