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MetaCyc Enzyme: flavonoid O-methyltransferase

Gene: OMT2 Accession Number: G-12214 (MetaCyc)

Species: Triticum aestivum

Summary:
A cDNA clone was isolated from wheat leaf cDNA database. The cDNA encodes a gene called TaOMT2 whose product sequentially methylates tricetin. The methylated products were identified by thin layer chromatography and they are; 3'-O-methyltricetin, 3',5'-O-dimethyltricetin and 3',4',5'-O-trimethyltricetin [Zhou06]. This single enzyme thus catalyzes the biosynthesis of tricin, tricetin and 3',4',5' -trimethyl ether.

Molecular Weight of Polypeptide: 38.5 kD (from nucleotide sequence), 38.5 kD (experimental) [Zhou06 ]

Unification Links: Entrez-Nucleotide:DQ223971 , Entrez:ABB03907 , Protein Model Portal:Q38J50 , SMR:Q38J50 , UniProt:Q38J50

Relationship Links: InterPro:IN-FAMILY:IPR001077 , InterPro:IN-FAMILY:IPR011991 , InterPro:IN-FAMILY:IPR012967 , InterPro:IN-FAMILY:IPR016461 , Pfam:IN-FAMILY:PF00891 , Pfam:IN-FAMILY:PF08100 , Prosite:IN-FAMILY:PS51683

Gene-Reaction Schematic: ?

Credits:
Created 01-Oct-2010 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: flavonoid O-methyltransferase

S-adenosyl-L-methionine + 3',5'-O-dimethyltricetin <=> S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: O -methylation of tricetin


Enzymatic reaction of: flavonoid O-methyltransferase

EC Number: 2.1.1.-

S-adenosyl-L-methionine + 3'-O-methyltricetin <=> S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: O -methylation of tricetin


Enzymatic reaction of: flavonoid O-methyltransferase

EC Number: 2.1.1.-

tricetin + S-adenosyl-L-methionine <=> 3'-O-methyltricetin + S-adenosyl-L-homocysteine + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: O -methylation of tricetin


References

Zhou06: Zhou JM, Gold ND, Martin VJ, Wollenweber E, Ibrahim RK (2006). "Sequential O-methylation of tricetin by a single gene product in wheat." Biochim Biophys Acta 1760(7);1115-24. PMID: 16730127


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Mar 5, 2015, BIOCYC14A.