Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate phosphatase

Species: Streptomyces griseus

Summary:
The subunit structure of this enzyme has not been reported.

Gene-Reaction Schematic: ?

Credits:
Created 15-Dec-2009 by Fulcher CA , SRI International


Enzymatic reaction of: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate phosphatase

EC Number: 3.1.3.40

1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-guanidino-1-deoxy-scyllo-inositol + phosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is physiologically favored in the direction shown.

Alternative Substrates for 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate: N1-amidinostreptamine 6-phosphate [Walker71 ]

In Pathways: streptomycin biosynthesis

Summary:
Enzyme activity was inhibited by sulfhydryl reagents [Walker71].

Cofactors or Prosthetic Groups: Mg2+ [Walker71]

Activators (Unknown Mechanism): dithiothreitol [Walker71]

Inhibitors (Unknown Mechanism): phosphate [Walker71]


References

Walker71: Walker MS, Walker JB (1971). "Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate." J Biol Chem 246(22);7034-40. PMID: 4331203


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC14B.