MetaCyc Enzyme: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate phosphatase

Species: Streptomyces griseus

The subunit structure of this enzyme has not been reported.

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Created 15-Dec-2009 by Fulcher CA , SRI International

Enzymatic reaction of: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate phosphatase

EC Number:

1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-guanidino-1-deoxy-scyllo-inositol + phosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

Alternative Substrates for 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate: N1-amidinostreptamine 6-phosphate [Walker71 ]

In Pathways: streptomycin biosynthesis

Enzyme activity was inhibited by sulfhydryl reagents [Walker71].

Cofactors or Prosthetic Groups: Mg2+ [Walker71]

Activators (Unknown Mechanism): dithiothreitol [Walker71]

Inhibitors (Unknown Mechanism): phosphate [Walker71]


Walker71: Walker MS, Walker JB (1971). "Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate." J Biol Chem 246(22);7034-40. PMID: 4331203

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri May 22, 2015, biocyc12.