MetaCyc Enzyme: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate phosphatase

Species: Streptomyces griseus

The subunit structure of this enzyme has not been reported.

Gene-Reaction Schematic

Gene-Reaction Schematic

Created 15-Dec-2009 by Fulcher CA, SRI International

Enzymatic reaction of: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate phosphatase

Inferred from experiment

EC Number:

1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O → 1-guanidino-1-deoxy-scyllo-inositol + phosphate

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

Alternative Substrates for 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate: N1-amidinostreptamine 6-phosphate [Walker71]

In Pathways: streptomycin biosynthesis

Enzyme activity was inhibited by sulfhydryl reagents [Walker71].

Cofactors or Prosthetic Groups: Mg2+ [Walker71]

Activators (Unknown Mechanism): L-dithiothreitol [Walker71] Inhibitors (Unknown Mechanism): phosphate [Walker71]


Walker71: Walker MS, Walker JB (1971). "Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate." J Biol Chem 246(22);7034-40. PMID: 4331203

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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