Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: nicotianamine synthase

Gene: OsNAS3 Accession Number: G-10641 (MetaCyc)

Synonyms: nicotianamine synthase 3

Species: Oryza

Summary:
A cDNA clone was isolated from rice seedling. The cDNA was recombinantly expressed in transgenic rice plants. The protein was shown to be a nicotianamine synthase and catalyzes the trimerization of SAM into nicotamine [Higuchi01].

Molecular Weight of Polypeptide: 36.9 kD (from nucleotide sequence), 36.9 kD (experimental) [Higuchi01 ]

Unification Links: ArrayExpress:A2YQ58 , Entrez:BAB17824 , Pride:A2YQ58 , Protein Model Portal:A2YQ58 , UniProt:A2YQ58

Relationship Links: Entrez-Nucleotide:PART-OF:AB023819 , InterPro:IN-FAMILY:IPR004298 , Pfam:IN-FAMILY:PF03059 , Prosite:IN-FAMILY:PS51142

Gene-Reaction Schematic: ?

Credits:
Created 06-May-2008 by Pujar A , Cornell University


Enzymatic reaction of: nicotianamine synthase

EC Number: 2.5.1.43

3 S-adenosyl-L-methionine <=> nicotianamine + 3 S-methyl-5'-thioadenosine + 3 H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

In Pathways: nicotianamine biosynthesis , 2'-deoxymugineic acid phytosiderophore biosynthesis


References

Higuchi01: Higuchi K, Watanabe S, Takahashi M, Kawasaki S, Nakanishi H, Nishizawa NK, Mori S (2001). "Nicotianamine synthase gene expression differs in barley and rice under Fe-deficient conditions." Plant J 25(2);159-67. PMID: 11169192


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13B.