|Gene:||OSCPNX1||Accession Number: G-10241 (MetaCyc)|
Synonyms: CAS, oxidosqualene cyclase
Species: Panax ginseng
A cDNA was isolated from suspended cells of hairy roots of Panax ginseng. The cDNA was recombinantly expressed in yeast cells and the molecular weight of the protein was calculated to be 86 kDa [Kushiro98]. The protein was shown to catalyze the conversion of (3S)-2,3-epoxy-2,3-dihydrosqualene to cycloartenol [Kushiro98].
Molecular Weight of Polypeptide: 86.0 kD (from nucleotide sequence)
Relationship Links: Entrez-Nucleotide:PART-OF:AB009029 , InterPro:IN-FAMILY:IPR001330 , InterPro:IN-FAMILY:IPR002365 , InterPro:IN-FAMILY:IPR008930 , InterPro:IN-FAMILY:IPR018333 , Pfam:IN-FAMILY:PF00432 , Prosite:IN-FAMILY:PS01074
|Molecular Function:||GO:0016871 - cycloartenol synthase activity [Kushiro98]|
Enzymatic reaction of: cycloartenol synthase
EC Number: 220.127.116.11
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
The reaction is favored in the direction shown.
Kushiro98: Kushiro T, Shibuya M, Ebizuka Y (1998). "β-amyrin synthase--cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants." Eur J Biochem 256(1);238-44. PMID: 9746369
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493