MetaCyc Enzyme: NMN nucleosidase

Species: Nicotiana tabacum

The enzyme activity of NMN nucleosidase (synonym NMN glycohydrolase - NMN-Ghase) has been detected in roots [Wagner86] and induced callus cultures of Nicotiana tabacum [Wagner86a]. The partially purified NMN-Ghase from tobacco catalyzed the formation of nicotinamide through hydrolysis of nicotinamide mononucleotide (NMN) with high efficiency [Wagner86b].

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Created 24-Oct-2006 by Foerster H , TAIR

Enzymatic reaction of: NMN nucleosidase

Synonyms: NMN glycohydrolase

EC Number:

β-nicotinamide D-ribonucleotide + H2O <=> D-ribofuranose 5-phosphate + nicotinamide + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: pyridine nucleotide cycling (plants)

Kinetic Parameters:

Km (μM)
β-nicotinamide D-ribonucleotide


Wagner86: Wagner R, Feth F, Wagner KG (1986). "The regulation of enzyme activities of the nicotine pathway in tobacco." Physiol. Plantarum, 68, 667-672.

Wagner86a: Wagner R, Feth F, Wagner KG (1986). "Regulation in tobacco callus of enzyme activities of the nicotine pathway II. The pyridine-nucleotide cycle ." Planta,168, 408-413.

Wagner86b: Wagner R, Feth F, Wagner KG (1986). "The pyridine-nucleotide cycle in tobacco. Enzyme activities for the recycling of NAD." Planta,167, 226-232.

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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