|Gene:||POX2||Accession Number: AT5G38710|
Species: Arabidopsis thaliana col
Arabidopsis has two functional genes encoding proline dehydrogenase - POX1 and POX2 [Funck10]. The two proteins have non-redundant, although partially overlapping physiological functions. Proline dehydrogenase 1 appears to be the dominant isoform under most conditions and in most tissues, while proline dehydrogenase 2 is specifically upregulated during salt stress (when POX1 is repressed) [Funck10].
proline dehydrogenase 2 is expressed in the vascular tissue and in the abscission zone of petals, sepals, stamina, pistils and siliques. It is Down-regulated by high succrose and up-regulated by L-proline and drought. When expressed in yeast the protein rescued the Pro metabolism defect of a Δput1 mutant strain [Funck10].
|Map Position: [15,518,475 -> 15,521,339]|
Molecular Weight of Polypeptide: 53.074 kD (from nucleotide sequence)
Unification Links: Entrez-gene:833862 , PhylomeDB:Q6NKX1 , Phytozome Plant Orthologs:AT5G38710.1 , Pride:Q6NKX1 , Protein Model Portal:Q6NKX1 , SMR:Q6NKX1 , String:3702.AT5G38710.1-P , TAIR:AT5G38710 , UniProt:Q6NKX1
Instance reactions of [L-proline + an electron-transfer quinone[inner membrane] → (S)-1-pyrroline-5-carboxylate + an electron-transfer quinol[inner membrane] + H+] (126.96.36.199):
|Cellular Component:||GO:0005739 - mitochondrion [Funck10]|
Enzymatic reaction of: proline dehydrogenase
EC Number: 188.8.131.52
Cofactors or Prosthetic Groups: FAD
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