MetaCyc Compound: W+6

Synonyms: tungsten ion

Superclasses: an iona cationan inorganic cation
an ionan inorganic ionan inorganic cation

Molecular Weight: 183.85 Daltons

Monoisotopic Molecular Weight: 183.9509326 Daltons

SMILES: [W++++++]

InChI: InChI=1S/W/q+6


Unification Links: ChEBI:49955, ChemSpider:22403, HMDB:HMDB01989, KEGG:C00753, PubChem:23964

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -11.234138Inferred by computational analysis [Latendresse13]

Enzymes activated by W+6, sorted by the type of activation, are:

Activator (Mechanism unknown) of: hydrogenase [Juszczak91]

This compound has been characterized as a cofactor or prosthetic group of the following enzymes: acetylene hydratase, NAD-dependent formate dehydrogenase, NAD-dependent formate dehydrogenase, NADP-dependent formate dehydrogenase, glyceraldehyde-3-phosphate ferredoxin oxidoreductase


Juszczak91: Juszczak A, Aono S, Adams MW (1991). "The extremely thermophilic eubacterium, Thermotoga maritima, contains a novel iron-hydrogenase whose cellular activity is dependent upon tungsten." J Biol Chem 1991;266(21);13834-41. PMID: 1649830

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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