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MetaCyc Gene-Ontology-Terms Class: GO:0016853 - isomerase activity

Definition: Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.

Summary:
Note that enzymes of class EC:5.99.-.- should also be annotated to this term.

Parent Classes:
GO:0003824 - catalytic activity

Child Classes:
GO:0003916 - DNA topoisomerase activity (4) ,
GO:0008719 - dihydroneopterin triphosphate 2'-epimerase activity (1) ,
GO:0016854 - racemase and epimerase activity (27) ,
GO:0016859 - cis-trans isomerase activity (8) ,
GO:0016860 - intramolecular oxidoreductase activity (38) ,
GO:0016866 - intramolecular transferase activity (43) ,
GO:0016872 - intramolecular lyase activity (1) ,
GO:0051075 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (1) ,
GO:0061593 - sulfoquinovose isomerase activity (1)

Term Members:
FabA ,
alanine racemase 1, PLP-binding, biosynthetic (alr) ,
DadX ,
phosphopentomutase (deoB) ,
D-arabinose 5-phosphate isomerase (kdsD) ,
D-arabinose 5-phosphate isomerase (gutQ) ,
glutamate racemase (murI) ,
UDP-N-acetylglucosamine 2-epimerase (wecB) ,
XylA ,
L-xylulose 5-phosphate 3-epimerase (ulaE) ,
L-ribulose 5-phosphate 4-epimerase monomer (araD) ,
L-ribulose-5-phosphate 4-epimerase (sgbE) ,
L-ribulose 5-phosphate 4-epimerase (ulaF) ,
FadJ monomer ,
isopentenyl diphosphate isomerase (idi) ,
ScpA ,
DapF ,
indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC) ,
PheA ,
TyrA ,
mannose-6-phosphate isomerase (manA) ,
FucI ,
L-fucose mutarotase (fucU) ,
allulose-6-phosphate 3-epimerase (alsE) ,
phosphoglucomutase (pgm) ,
ribose pyranase (rbsD) ,
isochorismate synthase 1 (entC) ,
MenF ,
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmM) ,
triosephosphate isomerase monomer (tpiA) ,
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase monomer (gpmA) ,
L-rhamnose isomerase (rhaA) ,
L-rhamnose mutarotase ,
N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase (hisA) ,
PurE ,
phosphoglucosamine mutase (glmM) ,
Pgi ,
L-arabinose isomerase monomer (araA) ,
D-glucuronate isomerase / D-galacturonate isomerase (uxaC) ,
UDP-glucose 4-epimerase monomer (galE) ,
Fcl ,
phosphomannomutase (cpsG) ,
glutamate-1-semialdehyde aminotransferase (hemL) ,
dihydroneopterin triphosphate 2'-epimerase monomer (folX) ,
ribulose-5-phosphate 3-epimerase (rpe) ,
allose-6-phosphate isomerase / ribose-5-phosphate isomerase B monomer (rpiB) ,
ribose-5-phosphate isomerase A (rpiA) ,
S-adenosylmethionine:tRNA ribosyltransferase-isomerase (queA) ,
L-Ala-D/L-Glu epimerase (ycjG) ,
UDP-galactopyranose mutase (glf) ,
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD) ,
D-sedoheptulose 7-phosphate isomerase (lpcA) ,
galactose-1-epimerase (galM) ,
phospho-AI-2 isomerase (lsrG) ,
predicted 5-keto 4-deoxyuronate isomerase monomer (kduI) ,
tRNA pseudouridine synthase I (truA) ,
β-phosphoglucomutase (ycjU) ,
23S rRNA pseudouridine 2604 synthase (rluF) ,
23S rRNA pseudouridine synthase (rluC) ,
fumarase A monomer ,
tRNA pseudouridine 13 synthase (truD) ,
lysine 2,3-aminomutase (epmB) ,
23S rRNA pseudouridine 2457 synthase (rluE) ,
DNA gyrase, subunit B (gyrB) ,
DNA gyrase, subunit A ,
23S rRNA pseudouridine synthase (rluD) ,
peptidyl-prolyl cis-trans isomerase A (rotamase A) (ppiA) ,
FKBP-type peptidyl prolyl cis-trans isomerase (slyD) ,
FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (fklB) ,
peptidyl-prolyl cis-trans isomerase B (rotamase B) (ppiB) ,
peptidyl-prolyl cis-trans isomerase C (rotamase C) (ppiC) ,
peptidyl-prolyl cis-trans isomerase (fkpB) ,
peptidyl-prolyl cis-trans isomerase (PPIase) (surA) ,
chaperone protein Tig; trigger factor ,
tRNA pseudouridine 65 synthase (truC) ,
23S rRNA and tRNA pseudouridine synthase (rluA) ,
NAD(P)HX epimerase / NAD(P)HX dehydratase (yjeF) ,
N-acetylneuraminate mutarotase (nanM) ,
Hyi ,
16S rRNA pseudouridine 516 synthase (rsuA) ,
dodecenoyl-CoA δ-isomerase, enoyl-CoA hydratase, 3-hydroxybutyryl-CoA epimerase, 3-hydroxyacyl-CoA dehydrogenase (fadB) ,
DNA topoisomerase I (topA) ,
DNA topoisomerase III (topB) ,
sulfoquinovose isomerase (yihS) ,
23S rRNA pseudouridine 2605 synthase (rluB) ,
dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC) ,
tRNA pseudouridine 55 synthase (truB) ,
3,2-trans-enoyl-CoA isomerase 2 (PECI) ,
Maleylacetoacetate isomerase (GSTZ1) ,
Methylmalonyl-CoA mutase, mitochondrial ,
phosphoglucomutase-1 (PGM1) ,
thromboxane-A synthase (TBXAS1) ,
hematopoietic prostaglandin D synthase (HPGDS) ,
prostaglandin-D2 synthase (PTGDS) ,
prostacyclin synthase (PTGIS) ,
Triosephosphate isomerase (TPI1) ,
phosphoglycerate mutase 2 (PGAM2) ,
Bisphosphoglycerate mutase (BPGM) ,
scyllo-inosose epimerase/isomerase (iolI) ,
5-deoxy-D-glucuronate isomerase (iolB) ,
phosphoglycerate mutase 1 (PGAM1) ,
glucose-6-phosphate isomerase (GPI) ,
peroxisomal bifunctional enzyme (EHHADH) ,
α-methylacyl-CoA racemase (AMACR) ,
3 β-hydroxysteroid dehydrogenase/ Δ 5-->4-isomerase type 1 (HSD3B1) ,
Steroid Delta-isomerase (HSD3B2)

Unification Links: GO:0016853


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Aug 29, 2015, BIOCYC14B.