MetaCyc Gene-Ontology-Terms Class: GO:0006635 - fatty acid beta-oxidation

Definition: A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).

Parent Classes:
GO:0019395 - fatty acid oxidation ,
GO:0009062 - fatty acid catabolic process

Child Classes:
GO:0033539 - fatty acid beta-oxidation using acyl-CoA dehydrogenase (1) ,
GO:0033542 - fatty acid beta-oxidation, unsaturated, even number (2)

Term Members:
FadD ,
acyl-CoA dehydrogenase (fadE) ,
FadI monomer ,
FadJ monomer ,
thioesterase III (fadM) ,
3-ketoacyl-CoA thiolase (fadA) ,
dodecenoyl-CoA δ-isomerase, enoyl-CoA hydratase, 3-hydroxybutyryl-CoA epimerase, 3-hydroxyacyl-CoA dehydrogenase (fadB) ,
carnitine O-palmitoyltransferase 2 (CPT2) ,
mitochondrial enoyl-CoA hydratase (ECHS1) ,
trifunctional enzyme beta subunit, mitochondrial precursor (HADHB) ,
peroxisomal acyl-coenzyme A oxidase 2 (ACOX2) ,
peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) ,
very-long-chain acyl-CoA dehydrogenase monomer (ACADVL) ,
short-chain acyl-CoA dehydrogenase monomer (ACADS) ,
mitochondrial medium-chain acyl-CoA dehydrogenase monomer (ACADM)

Unification Links: GO:0006635

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 13, 2015, biocyc13.