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MetaCyc Gene-Ontology-Terms Class: GO:0005887 - integral component of plasma membrane

Definition: The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Parent Classes:
GO:0016021 - integral component of membrane,
GO:0031226 - intrinsic component of plasma membrane

Child Classes:
GO:0071575 - integral component of external side of plasma membrane (9)

Term Members:
protein disulfide oxidoreductase - DsbDreduced,
penicillin-binding protein 6 (dacC),
cell shape; peptidoglycan synthetase; penicillin-binding protein 2 (mrdA),
essential cell division protein FtsI; penicillin-binding protein 3,
DD-carboxypeptidase, penicillin-binding protein 6b (dacD),
predicted Wzy protein involved in ECA polysaccharide chain elongation (wzyE),
predicted PTS permease - FrwC subunit,
fructose PTS permease - FruA subunit,
predicted PTS permease - SgcC subunit,
formate dehydrogenase N, γ subunit (fdnI),
formate dehydrogenase-O, γ subunit (fdoI),
GlpD,
MrcA,
pyridine nucleotide transhydrogenase,
pyridine nucleotide transhydrogenase, α subunit (pntA),
pyridine nucleotide transhydrogenase, β subunit (pntB),
D-lactate dehydrogenase (dld),
phosphatidylglycerophosphate synthase (pgsA),
phosphatidylglycerophosphatase A (pgpA),
phosphatidylglycerophosphatase C (pgpC),
1,4-dihydroxy-2-naphthoate octaprenyltransferase (menA),
Rfe,
fumarate reductase,
fumarate reductase membrane protein (frdD),
glycerol-3-phosphate acyltransferase (plsB),
cytochrome bo terminal oxidase,
cytochrome bo terminal oxidase subunit III (cyoC),
cytochrome bo terminal oxidase subunit I (cyoB),
cytochrome bo terminal oxidase subunit II (cyoA),
cytochrome bo terminal oxidase subunit IV (cyoD),
cytochrome bd-I terminal oxidase,
cytochrome bd-I terminal oxidase - CydX subunit,
cytochrome bd-I terminal oxidase subunit II (cydB),
cytochrome bd-I terminal oxidase subunit I (cydA),
trimethylamine N-oxide reductase, c-type cytochrome subunit (torY),
dimethyl sulfoxide reductase, chain C (dmsC),
hydrogenase 2 - integral membrane subunit HybB,
hydrogenase 2 - [Fe-S] binding, ferredoxin-type component HybA,
NADH:ubiquinone oxidoreductase, membrane subunit N (nuoN),
NADH:ubiquinone oxidoreductase, membrane subunit M (nuoM),
NADH:ubiquinone oxidoreductase, membrane subunit L (nuoL),
NADH:ubiquinone oxidoreductase, membrane subunit K (nuoK),
NADH:ubiquinone oxidoreductase, membrane subunit J (nuoJ),
NADH:ubiquinone oxidoreductase, membrane subunit H (nuoH),
NADH:ubiquinone oxidoreductase, membrane subunit A (nuoA),
lauroyl acyltransferase (lpxL),
palmitoleoyl acyltransferase (lpxP),
myristoyl-acyl carrier protein (ACP)-dependent acyltransferase (lpxM),
inner membrane protein with thiosulfate sulfurtransferase activity (ygaP),
protease IV (sppA),
leader peptidase (signal peptidase I) (lepB),
nitrate reductase A, γ subunit (narI),
hydrogenase 1, b-type cytochrome subunit (hyaC),
NADH:quinone oxidoreductase II (ndh),
phosphoethanolamine transferase (opgE),
protein-tyrosine kinase (wzc),
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase (lgt),
formate-dependent nitrite reductase, 4Fe-4S subunit (nrfC),
formate dependent nitrite reductase - NrfD subunit,
membrane-bound lytic murein transglycosylase A (mltA),
phosphatidylglycerophosphatase [multifunctional] (pgpB),
D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (dacA),
HflK-HflC complex; regulator of FtsH protease,
hydrogenase 3,
hydrogenase 3, membrane subunit (hycD),
penicillin-binding protein 7 (pbpG),
murein DD-endopeptidase MepM,
intramembrane serine protease GlpG,
phosphopantetheinyl transferase (entD),
MalX PTS permease,
poly-β-1,6-N-acetyl-D-glucosamine synthase,
poly-β-1,6-N-acetyl-D-glucosamine synthase - PgaC subunit,
poly-β-1,6-N-acetyl-D-glucosamine synthase - PgaD subunit,
NagE,
2-O-α-mannosyl-D-glycerate PTS permease (mngA),
chitobiose PTS permease - ChbC subunit,
galactitol PTS permease - GatC subunit,
L-ascorbate PTS permease - UlaA subunit,
glucose PTS permease - PtsG subunit,
mannose PTS permease - ManX subunit,
mannose PTS permease - ManY subunit,
mannose PTS permease - ManZ subunit,
trehalose PTS permease - TreB subunit,
N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease (murP),
predicted PTS permease - CmtA subunit,
MtlA,
sorbitol PTS permease - SrlE subunit,
sorbitol PTS permease - SrlA subunit,
ABC complex for formation and release of holoCcmE - membrane subunit CcmC,
ABC complex for formation and release of holoCcmE - membrane subunit CcmB,
ABC complex for formation and release of holoCcmE - membrane subunit CcmD,
dipeptide ABC transporter - putative membrane subunit (dppC),
dipeptide ABC transporter - putative membrane subunit (dppB),
glutathione ABC transporter - membrane subunit (gsiC),
glutathione ABC transporter - membrane subunit (gsiD),
phosphate ABC transporter - membrane subunit (pstC),
phosphate ABC transporter - membrane subunit (pstA),
ATP synthase F0 complex - a subunit (atpB),
Cu+ efflux ATPase (copA),
L-arginine ABC transporter - membrane subunit (artM),
L-arginine ABC transporter - membrane subunit (artQ),
K+ transporting ATPase - KdpC subunit,
K+ transporting ATPase - ATP binding subunit (kdpB),
K+ transporting ATPase - K+ channel forming subunit (kdpA),
maltose ABC transporter - membrane subunit (malG),
maltose ABC transporter - membrane subunit (malF),
aliphatic sulfonate ABC transporter - membrane subunit (ssuC),
glycerol-3-phosphate / glycerophosphodiester ABC transporter,
glycerol-3-phosphate ABC transporter - membrane subunit (ugpE),
glycerol-3-phosphate ABC transporter - membrane subunit (ugpA),
zinc, cadmium and lead efflux system (zntA),
L-cystine ABC transporter - predicted membrane subunit (tcyL),
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit (oppC),
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit (oppB),
nickel ABC transporter - membrane subunit (nikC),
nickel ABC transporter - membrane subunit (nikB),
glutathione / L-cysteine efflux transporter CydDC,
glutathione / L-cysteine efflux transporter - CydC subunit,
glutathione / L-cysteine efflux transporter - CydD subunit,
α-ketoglutarate:H+ symporter (kgtP),
4-aminobutyrate:H+ symporter (gabP),
nitrate / nitrite transporter NarU,
ArsB monomer,
uracil:H+ symporter UraA,
uracil:H+ symporter RutG,
putrescine:H+ symporter PuuP,
putrescine:H+ symporter PlaP,
tryptophan:H+ symporter TnaB,
dipeptide / tripeptide:H+ symporter DtpB,
dipeptide / tripeptide:H+ symporter DptC (dtpC),
dipeptide:H+ symporter DtpD,
tripeptide / dipeptide:H+ symporter DtpA,
glutamic acid:4-aminobutyrate antiporter (gadC),
phenylalanine:H+ symporter PheP,
arabinose:H+ symporter (araE),
3-hydroxyphenylpropionate / 3-hydroxycinnamate:H+ symporter (mhpT),
choline:H+ symporter (betT),
(R)-lactate / (S)-lactate / glycolate:H+ symporter LldP,
glycolate / lactate:H+ symporter (glcA),
cytosine transporter (codB),
ProP,
cadaverine:H+ symporter / lysine:cadaverine antiporter (cadB),
multidrug / spermidine efflux transporter - membrane subunit MdtI,
multidrug / spermidine efflux transporter - membrane subunit MdtJ,
nucleoside:H+ symporter NupG,
xylose:H+ symporter (xylE),
putrescine:H+ symporter / putrescine:ornithine antiporter PotE,
galactose:H+ symporter (galP),
acetate / succinate:H+ symporter (satP),
xanthine:H+ symporter XanP,
xanthine:H+ symporter XanQ,
urate:H+ symporter (uacT),
hexuronate transporter (exuT),
shikimate:H+ symporter (shiA),
K+ : H+ antiporter KefB,
KefC,
O-Acetylserine / cysteine export protein (eamB),
lactose / melibiose:H+ symporter LacY,
lysine:H+ symporter (lysP),
Zn2+ / Fe2+ / Cd2+ efflux transporter FieF,
AdiC monomer,
Na+ / K+:H+ antiporter ChaA,
multidrug efflux transporter MdfA (multifunctional),
multidrug efflux transporter / bile salt:H+ antiporter / Na+:H+ antiporter / K+:H+ antiporter (mdtM),
twin arginine protein translocation system - TatA protein,
twin arginine protein translocation system - TatE protein,
twin arginine protein translocation system - TatC protein,
twin arginine protein translocation system - TatB protein,
aromatic amino acid exporter (yddG),
melibiose:H+/Na+/Li+ symporter (melB),
ClcA,
tryptohan / indole:H+ symporter Mtr,
K+ transporter TrkG,
K+ transporter TrkH,
serine:H+ symporter SdaC,
serine / threonine:H+ symporter TdcC,
L-idonate / 5-ketogluconate / gluconate transporter IdnT,
gluconate transporter GntU,
gluconate transporter GntT,
gluconate / fructuronate transporter GntP,
L-methionine / branched chain amino acid efflux transporter (yjeH),
EmrE,
nucleoside:H+ symporter NupC,
C4 dicarboxylate / orotate:H+ symporter (dctA),
hexose-6-phosphate:phosphate antiporter (uhpT),
aromatic amino acid:H+ symporter AroP,
adenine:H+ symporter (adeP),
metal phosphate:H+ symporter PitB,
N-acetylneuraminate:H+ symporter (nanT),
serine / alanine / glycine / cycloserine:H+symporter (cycA),
vitamin B12 ABC transporter,
vitamin B12 ABC transporter - membrane subunit (btuC),
ferric enterobactin ABC transporter - membrane subunit (fepD),
ferric enterobactin ABC transporter - membrane subunit (fepG),
FocA,
nitrite transporter NirC,
nitrate:nitrite antiporter NarK,
AmtB monomer,
GlpF,
AqpZ monomer,
proline:Na+ symporter (putP),
cystine efflux transporter (yijE),
L-alanine exporter (alaE),
lipid II flippase (murJ),
essential cell division protein FtsW; lipid II flippase,
L-lysine efflux transporter (lysO),
nicotinamide riboside transporter (pnuC),
adenine transporter (adeQ),
L-arginine efflux transporter (argO),
Ni2+ / Co2+ / Mg2+ transporter (corA),
LptC,
ActP monomer,
manganese export protein (mntP),
F- efflux transporter / involved in resistance to camphor-induced chromosome decondensation (crcB),
C4 dicarboxylate / C4 monocarboxylate transporter DauA,
FMN / FAD exporter (yeeO),
putative inorganic phosphate export protein (yjbB),
fructoselysine / psicoselysine transporter (frlA),
S-methyl-L-methionine transporter (mmuP),
guanine / hypoxanthine transporter GhxP,
guanine / hypoxanthine transporter GhxQ,
tellurite resistance protein / ethidium efflux transporter (tehA),
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnF subunit,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnE subunit,
sphingolipid 4-desaturase 1 (DEGS1),
N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase (B3GNT1),
β-1,3-galactosyl-O-glycosyl-[glycoprotein] β-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3),
ectonucleoside triphosphate diphosphohydrolase 1 monomer (ENTPD1),
Y+L amino acid transporter 2 (SLC7A6),
large neutral amino acids transporter small subunit 2 (SLC7A8),
retinol dehydrogenase 8 (RDH8),
acyl-CoA 4/6/8-desaturase (FADS2)

Unification Links: GO:0005887


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun Feb 7, 2016, biocyc12.