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MetaCyc Gene-Ontology-Terms Class: GO:0005887 - integral component of plasma membrane

Definition: The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Parent Classes:
GO:0016021 - integral component of membrane ,
GO:0031226 - intrinsic component of plasma membrane ,
GO:0044459 - plasma membrane part

Child Classes:
GO:0071575 - integral component of external side of plasma membrane (8)

Term Members:
protein disulfide oxidoreductase - DsbDreduced ,
predicted Wzy protein involved in ECA polysaccharide chain elongation (wzyE) ,
cell shape; peptidoglycan synthetase; penicillin-binding protein 2 (mrdA) ,
essential cell division protein FtsI; penicillin-binding protein 3 ,
DD-carboxypeptidase, penicillin-binding protein 6b (dacD) ,
penicillin-binding protein 6 (dacC) ,
fructose PTS permease - FruA subunit ,
predicted PTS permease - SgcC subunit ,
predicted PTS permease - FrwC subunit ,
lauroyl acyltransferase (lpxL) ,
palmitoleoyl acyltransferase (lpxP) ,
myristoyl-acyl carrier protein (ACP)-dependent acyltransferase (lpxM) ,
Rfe ,
formate dehydrogenase N, γ subunit (fdnI) ,
formate dehydrogenase-O, γ subunit (fdoI) ,
hydrogenase 2 - integral membrane subunit HybB ,
hydrogenase 2 - [Fe-S] binding, ferredoxin-type component HybA ,
fumarate reductase ,
fumarate reductase membrane protein (frdD) ,
trimethylamine N-oxide reductase, c-type cytochrome subunit (torY) ,
dimethyl sulfoxide reductase, chain C (dmsC) ,
GlpD ,
D-lactate dehydrogenase (dld) ,
1,4-dihydroxy-2-naphthoate octaprenyltransferase (menA) ,
pyridine nucleotide transhydrogenase ,
pyridine nucleotide transhydrogenase, α subunit (pntA) ,
pyridine nucleotide transhydrogenase, β subunit (pntB) ,
inner membrane protein with thiosulfate sulfurtransferase activity (ygaP) ,
glycerol-3-phosphate acyltransferase (plsB) ,
phosphatidylglycerophosphate synthase (pgsA) ,
phosphatidylglycerophosphatase A (pgpA) ,
phosphatidylglycerophosphatase C (pgpC) ,
MrcA ,
cytochrome bo terminal oxidase ,
cytochrome bo terminal oxidase subunit III (cyoC) ,
cytochrome bo terminal oxidase subunit I (cyoB) ,
cytochrome bo terminal oxidase subunit II (cyoA) ,
cytochrome bo terminal oxidase subunit IV (cyoD) ,
NADH:ubiquinone oxidoreductase, membrane subunit N (nuoN) ,
NADH:ubiquinone oxidoreductase, membrane subunit M (nuoM) ,
NADH:ubiquinone oxidoreductase, membrane subunit L (nuoL) ,
NADH:ubiquinone oxidoreductase, membrane subunit K (nuoK) ,
NADH:ubiquinone oxidoreductase, membrane subunit J (nuoJ) ,
NADH:ubiquinone oxidoreductase, membrane subunit H (nuoH) ,
NADH:ubiquinone oxidoreductase, membrane subunit A (nuoA) ,
cytochrome bd-I terminal oxidase ,
cytochrome bd-I terminal oxidase - CydX subunit ,
cytochrome bd-I terminal oxidase subunit II (cydB) ,
cytochrome bd-I terminal oxidase subunit I (cydA) ,
leader peptidase (signal peptidase I) (lepB) ,
penicillin-binding protein 7 (pbpG) ,
murein DD-endopeptidase MepM ,
protein-tyrosine kinase (wzc) ,
intramembrane serine protease GlpG ,
nitrate reductase A, γ subunit (narI) ,
protease IV (sppA) ,
NADH:quinone oxidoreductase II (ndh) ,
phosphoethanolamine transferase (opgE) ,
D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (dacA) ,
hydrogenase 1, b-type cytochrome subunit (hyaC) ,
membrane-bound lytic murein transglycosylase A (mltA) ,
hydrogenase 3 ,
hydrogenase 3, membrane subunit (hycD) ,
phosphopantetheinyl transferase (entD) ,
formate-dependent nitrite reductase, 4Fe-4S subunit (nrfC) ,
formate dependent nitrite reductase - NrfD subunit ,
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase (lgt) ,
HflK-HflC complex; regulator of FtsH protease ,
phosphatidylglycerophosphatase [multifunctional] (pgpB) ,
MalX PTS permease ,
poly-β-1,6-N-acetyl-D-glucosamine synthase ,
poly-β-1,6-N-acetyl-D-glucosamine synthase - PgaC subunit ,
poly-β-1,6-N-acetyl-D-glucosamine synthase - PgaD subunit ,
NagE ,
2-O-α-mannosyl-D-glycerate PTS permease (mngA) ,
chitobiose PTS permease - ChbC subunit ,
galactitol PTS permease - GatC subunit ,
L-ascorbate PTS permease - UlaA subunit ,
glucose PTS permease - PtsG subunit ,
mannose PTS permease - ManX subunit ,
mannose PTS permease - ManY subunit ,
mannose PTS permease - ManZ subunit ,
trehalose PTS permease - TreB subunit ,
N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease (murP) ,
predicted PTS permease - CmtA subunit ,
MtlA ,
sorbitol PTS permease - SrlE subunit ,
sorbitol PTS permease - SrlA subunit ,
phosphate ABC transporter - membrane subunit (pstA) ,
ATP synthase F0 complex - a subunit (atpB) ,
ABC complex for formation and release of holoCcmE - membrane subunit CcmC ,
ABC complex for formation and release of holoCcmE - membrane subunit CcmB ,
ABC complex for formation and release of holoCcmE - membrane subunit CcmD ,
L-arginine ABC transporter - membrane subunit (artM) ,
L-arginine ABC transporter - membrane subunit (artQ) ,
aliphatic sulfonate ABC transporter - membrane subunit (ssuC) ,
phosphonate ABC transporter - membrane subunit (phnE_1) ,
Cu+ efflux ATPase (copA) ,
glycerol-3-phosphate / glycerophosphodiester ABC transporter ,
glycerol-3-phosphate ABC transporter - membrane subunit (ugpE) ,
glycerol-3-phosphate ABC transporter - membrane subunit (ugpA) ,
glutathione / L-cysteine efflux transporter CydDC ,
glutathione / L-cysteine efflux transporter - CydC subunit ,
glutathione / L-cysteine efflux transporter - CydD subunit ,
L-cystine ABC transporter - predicted membrane subunit (yecS) ,
ArsB monomer ,
α-ketoglutarate:H+ symporter (kgtP) ,
putrescine:H+ symporter PuuP ,
putrescine:H+ symporter PlaP ,
tryptophan:H+ symporter TnaB ,
dipeptide / tripeptide:H+ symporter DtpB ,
dipeptide / tripeptide:H+ symporter DptC (dtpC) ,
dipeptide:H+ symporter DtpD ,
tripeptide / dipeptide:H+ symporter DtpA ,
ActP monomer ,
uracil:H+ symporter UraA ,
uracil:H+ symporter RutG ,
phenylalanine:H+ symporter PheP ,
glutamic acid:4-aminobutyrate antiporter (gadC) ,
3-hydroxyphenylpropionate / 3-hydroxycinnamate:H+ symporter (mhpT) ,
choline:H+ symporter (betT) ,
arabinose:H+ symporter (araE) ,
ProP ,
cadaverine:H+ symporter / lysine:cadaverine antiporter (cadB) ,
spermidine efflux transporter - MdtI subunit ,
(R)-lactate / (S)-lactate / glycolate:H+ symporter LldP ,
glycolate / lactate:H+ symporter (glcA) ,
xylose:H+ symporter (xylE) ,
putrescine:H+ symporter / putrescine:ornithine antiporter PotE ,
cytosine transporter (codB) ,
nucleoside:H+ symporter NupG ,
acetate / succinate:H+ symporter (satP) ,
K+ : H+ antiporter KefB ,
KefC ,
xanthine:H+ symporter XanP ,
xanthine:H+ symporter XanQ ,
urate:H+ symporter (uacT) ,
galactose:H+ symporter (galP) ,
lysine:H+ symporter (lysP) ,
Zn2+ / Fe2+ / Cd2+ efflux transporter FieF ,
O-Acetylserine / cysteine export protein (eamB) ,
hexuronate transporter (exuT) ,
shikimate:H+ symporter (shiA) ,
TatA ,
TatE ,
TatC ,
TatB ,
aromatic amino acid exporter (yddG) ,
AdiC monomer ,
Na+ / K+:H+ antiporter ChaA ,
multidrug efflux transporter MdfA (multifunctional) ,
multidrug efflux transporter / bile salt:H+ antiporter / Na+:H+ antiporter / K+:H+ antiporter (mdtM) ,
lactose / melibiose:H+ symporter LacY ,
K+ transporter TrkG ,
K+ transporter TrkH ,
serine:H+ symporter SdaC ,
serine / threonine:H+ symporter TdcC ,
gluconate transporter GntU ,
gluconate / fructuronate transporter GntP ,
EmrE ,
ClcA ,
aromatic amino acid:H+ symporter AroP ,
adenine:H+ symporter (adeP) ,
tryptohan / indole:H+ symporter Mtr ,
serine / alanine / glycine / cycloserine:H+symporter (cycA) ,
nucleoside:H+ symporter NupC ,
C4 dicarboxylate / orotate:H+ symporter (dctA) ,
N-acetylneuraminate:H+ symporter (nanT) ,
4-aminobutyrate:H+ symporter (gabP) ,
melibiose:H+/Na+/Li+ symporter (melB) ,
nitrate / nitrite transporter NarU ,
hexose-6-phosphate:phosphate antiporter (uhpT) ,
vitamin B12 ABC transporter ,
vitamin B12 ABC transporter - membrane subunit (btuC) ,
ferric enterobactin ABC transporter - membrane subunit (fepD) ,
ferric enterobactin ABC transporter - membrane subunit (fepG) ,
FocA ,
nitrate:nitrite antiporter NarK ,
AmtB monomer ,
GlpF ,
AqpZ monomer ,
proline:Na+ symporter (putP) ,
cystine efflux transporter (yijE) ,
L-alanine exporter (alaE) ,
lipid II flippase (murJ) ,
essential cell division protein FtsW; lipid II flippase ,
L-lysine efflux transporter (lysO) ,
nicotinamide riboside transporter (pnuC) ,
adenine transporter (adeQ) ,
L-arginine efflux transporter (argO) ,
Ni2+ / Co2+ / Mg2+ transporter (corA) ,
LptC ,
manganese export protein (mntP) ,
F- efflux transporter / involved in resistance to camphor-induced chromosome decondensation (crcB) ,
C4 dicarboxylate / C4 monocarboxylate transporter DauA ,
FMN / FAD exporter (yeeO) ,
putative inorganic phosphate export protein (yjbB) ,
fructoselysine / psicoselysine transporter (frlA) ,
S-methyl-L-methionine transporter (mmuP) ,
guanine / hypoxanthine transporter GhxP ,
guanine / hypoxanthine transporter GhxQ ,
tellurite resistance protein / ethidium efflux transporter (tehA) ,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnF subunit ,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnE subunit ,
sphingolipid 4-desaturase 1 (DEGS1) ,
N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase (B3GNT1) ,
β-1,3-galactosyl-O-glycosyl-[glycoprotein] β-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3) ,
ectonucleoside triphosphate diphosphohydrolase 1 monomer (ENTPD1) ,
Y+L amino acid transporter 2 (SLC7A6) ,
large neutral amino acids transporter small subunit 2 (SLC7A8) ,
retinol dehydrogenase 8 (RDH8) ,
acyl-CoA 6-desaturase (FADS2)

Unification Links: GO:0005887


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Aug 29, 2015, biocyc11.