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discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc EC 4.1.1 -- Carboxy-lyases

Parent Class: EC-Numbers 4 -- Lyases 4.1 -- Carbon-carbon lyases

Instances:
4.1.1.1 -- pyruvate decarboxylase ,
4.1.1.2 -- oxalate decarboxylase ,
4.1.1.3 -- oxaloacetate decarboxylase ,
4.1.1.4 -- acetoacetate decarboxylase ,
4.1.1.5 -- acetolactate decarboxylase ,
4.1.1.6 -- aconitate decarboxylase ,
4.1.1.7 -- benzoylformate decarboxylase ,
4.1.1.8 -- oxalyl-CoA decarboxylase ,
4.1.1.9 -- malonyl-CoA decarboxylase ,
4.1.1.11 -- aspartate 1-decarboxylase ,
4.1.1.12 -- aspartate 4-decarboxylase ,
4.1.1.14 -- valine decarboxylase ,
4.1.1.15 -- glutamate decarboxylase ,
4.1.1.16 -- hydroxyglutamate decarboxylase ,
4.1.1.17 -- ornithine decarboxylase ,
4.1.1.18 -- lysine decarboxylase ,
4.1.1.19 -- arginine decarboxylase ,
4.1.1.20 -- diaminopimelate decarboxylase ,
4.1.1.21 -- phosphoribosylaminoimidazole carboxylase ,
4.1.1.22 -- histidine decarboxylase ,
4.1.1.23 -- orotidine-5′-phosphate decarboxylase ,
4.1.1.24 -- aminobenzoate decarboxylase ,
4.1.1.25 -- tyrosine decarboxylase ,
4.1.1.28 -- aromatic-L-amino-acid decarboxylase ,
4.1.1.29 -- sulfinoalanine decarboxylase ,
4.1.1.30 -- pantothenoylcysteine decarboxylase ,
4.1.1.31 -- phosphoenolpyruvate carboxylase ,
4.1.1.32 -- phosphoenolpyruvate carboxykinase (GTP) ,
4.1.1.33 -- diphosphomevalonate decarboxylase ,
4.1.1.34 -- dehydro-L-gulonate decarboxylase ,
4.1.1.35 -- UDP-glucuronate decarboxylase ,
4.1.1.36 -- phosphopantothenoylcysteine decarboxylase ,
4.1.1.37 -- uroporphyrinogen decarboxylase ,
4.1.1.38 -- phosphoenolpyruvate carboxykinase (diphosphate) ,
4.1.1.39 -- ribulose-bisphosphate carboxylase ,
4.1.1.40 -- hydroxypyruvate decarboxylase ,
4.1.1.41 -- methylmalonyl-CoA decarboxylase ,
4.1.1.42 -- carnitine decarboxylase ,
4.1.1.43 -- phenylpyruvate decarboxylase ,
4.1.1.44 -- 4-carboxymuconolactone decarboxylase ,
4.1.1.45 -- aminocarboxymuconate-semialdehyde decarboxylase ,
4.1.1.46 -- o-pyrocatechuate decarboxylase ,
4.1.1.47 -- tartronate-semialdehyde synthase ,
4.1.1.48 -- indole-3-glycerol-phosphate synthase ,
4.1.1.49 -- phosphoenolpyruvate carboxykinase (ATP) ,
4.1.1.50 -- adenosylmethionine decarboxylase ,
4.1.1.51 -- 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase ,
4.1.1.52 -- 6-methylsalicylate decarboxylase ,
4.1.1.53 -- phenylalanine decarboxylase ,
4.1.1.54 -- dihydroxyfumarate decarboxylase ,
4.1.1.55 -- 4,5-dihydroxyphthalate decarboxylase ,
4.1.1.56 -- 3-oxolaurate decarboxylase ,
4.1.1.57 -- methionine decarboxylase ,
4.1.1.58 -- orsellinate decarboxylase ,
4.1.1.59 -- gallate decarboxylase ,
4.1.1.60 -- stipitatonate decarboxylase ,
4.1.1.61 -- 4-hydroxybenzoate decarboxylase ,
4.1.1.62 -- gentisate decarboxylase ,
4.1.1.63 -- protocatechuate decarboxylase ,
4.1.1.64 -- 2,2-dialkylglycine decarboxylase (pyruvate) ,
4.1.1.65 -- phosphatidylserine decarboxylase ,
4.1.1.66 -- uracil-5-carboxylate decarboxylase ,
4.1.1.67 -- UDP-galacturonate decarboxylase ,
4.1.1.68 -- 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase ,
4.1.1.69 -- 3,4-dihydroxyphthalate decarboxylase ,
4.1.1.70 -- glutaconyl-CoA decarboxylase ,
4.1.1.71 -- 2-oxoglutarate decarboxylase ,
4.1.1.72 -- branched-chain-2-oxoacid decarboxylase ,
4.1.1.73 -- tartrate decarboxylase ,
4.1.1.74 -- indolepyruvate decarboxylase ,
4.1.1.75 -- 5-guanidino-2-oxopentanoate decarboxylase ,
4.1.1.76 -- arylmalonate decarboxylase ,
4.1.1.77 -- 2-oxo-3-hexenedioate decarboxylase ,
4.1.1.78 -- acetylenedicarboxylate decarboxylase ,
4.1.1.79 -- sulfopyruvate decarboxylase ,
4.1.1.80 -- 4-hydroxyphenylpyruvate decarboxylase ,
4.1.1.81 -- threonine-phosphate decarboxylase ,
4.1.1.82 -- phosphonopyruvate decarboxylase ,
4.1.1.83 -- 4-hydroxyphenylacetate decarboxylase ,
4.1.1.84 -- D-dopachrome decarboxylase ,
4.1.1.85 -- 3-dehydro-L-gulonate-6-phosphate decarboxylase ,
4.1.1.86 -- diaminobutyrate decarboxylase ,
4.1.1.87 -- malonyl-S-ACP decarboxylase ,
4.1.1.88 -- biotin-independent malonate decarboxylase ,
4.1.1.89 -- biotin-dependent malonate decarboxylase ,
4.1.1.90 -- peptidyl-glutamate 4-carboxylase ,
4.1.1.91 -- salicylate decarboxylase ,
4.1.1.92 -- indole-3-carboxylate decarboxylase ,
4.1.1.93 -- pyrrole-2-carboxylate decarboxylase ,
4.1.1.94 -- ethylmalonyl-CoA decarboxylase ,
4.1.1.95 -- L-glutamyl-[BtrI acyl-carrier protein] decarboxylase ,
4.1.1.96 -- carboxynorspermidine decarboxylase ,
4.1.1.97 -- 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase ,
4.1.1.98 -- 4-hydroxy-3-polyprenylbenzoate decarboxylase

Unofficial Reactions:
2-oxopent-5-chloro-3-enoate + H+ → 2-oxo-5-chloro-4-pentenoate + CO2 ,
carboxyspermidine + H+ → spermidine + CO2 ,
5-chloro-4-hydroxy-2-oxopentanoate + an oxidized ferredoxin + coenzyme A → 4-chloro-3-hydroxybutyryl-CoA + CO2 + a reduced ferredoxin ,
a 3-oxoacid + H+ → a methylketone + CO2 ,
3-hexaprenyl-4-amino-5-methoxybenzoate + H+ → 2-hexaprenyl-6-methoxyaminobenzene + CO2 ,
10-carboxy-3-deoxycarminomycin + H+ → 13-deoxycarminomycin + CO2 ,
15-demethoxyaclacinomycin T + a reduced electron acceptor + H+ + oxygen = 10-decarboxymethylaclacinomycin T + CO2 + an oxidized electron acceptor + H2O ,
15-demethoxy-aclacinomycin A + a reduced electron acceptor + H+ + oxygen = 10-decarboxymethyl, 10-hydroxyaclacinomycin A + CO2 + an oxidized electron acceptor + H2O ,
15-demethoxy-ε-rhodomycinone + H+ → 15-decarboxymethyl-ε-rhodomycinone + CO2 ,
2-oxovalerate + H+ → butanal + CO2 ,
naphthalene + hydrogen carbonate = 2-naphthoate + H2O ,
3-carboxy-2-hydroxymuconate semialdehyde + H+ → (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + CO2 ,
3,6,8-trimethyl-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline → S-(+)-3,6,8-trimethylallantoin + CO2 + H+ ,
siroheme + 2 H+ → 12,18-didecarboxysiroheme + 2 CO2 ,
(-)-dehydrodiconiferyl acid carboxylate + H+ → 4,2'-dihydroxy-3,3'-dimethoxy-5'-(2''-carboxyvinyl)stilbene + CO2 ,
L-serine + H+ → ethanolamine + CO2 ,
2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate + H+ ↔ 2-hydroxy-6-oxo-7-methyl-octa-2,4-dienoate + CO2 ,
UDP-α-D-glucuronate + H+ → UDP-D-apiose + CO2 ,
ferulate + H+ ↔ 4-vinylguaiacol + CO2 ,
4-coumarate + H+ = 4-vinylphenol + CO2 ,
trans-cinnamate + H+ = styrene + CO2 ,
2-oxo-3-carboxy-4,5-cyclopropylhex-5-enoate + H+ → beta-methylenecyclopropyl pyruvate + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-octaprenyl)phenol + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-nonaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-nonaprenyl)phenol + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-heptaprenyl)phenol + CO2 ,
2-phosphoglycolate + 3-phospho-D-glycerate + 2 H+ ↔ D-ribulose-1,5-bisphosphate + oxygen ,
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H+ → 2-hexaprenyl-6-methoxyphenol + CO2

Enzymes and Genes:
ribulose-bisphosphate carboxylase : ATMG00280 ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase : cbbS , cbbL ( Synechocystis sp. PCC 6803 )
ribulose bisphosphate carboxylase/oxygenase : rbcS2B , ATCG00490 ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : rbcS3B , ATCG00490 ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : ATCG00490 , rbcS1A ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : rbcS1B , ATCG00490 ( Arabidopsis thaliana col )
phenolic acid decarboxylase : pad1 ( Bacillus subtilis )
ferulic acid decarboxylase : fdc1 ( Saccharomyces cerevisiae )
phenylacrylate decarboxylase : pad1 ( Saccharomyces cerevisiae )
UDP-D-xylose synthase / UDP-D-apiose synthase ( Petroselinum crispum )
UDP-D-apiose synthase / UDP-D-xylose synthase : AXS1 ( Arabidopsis thaliana col )
HCOMODA decarboxylase : cmtD ( Pseudomonas putida F1 )
serine decarboxylase ( Spinacia oleracea )
serine decarboxylase : AtSDC ( Arabidopsis thaliana col )
serine decarboxylase : BnSDC ( Brassica napus )
siroheme decarboxylase : ahbB , ahbA ( Desulfovibrio desulfuricans )
siroheme decarboxylase : nirH , nirG , nirD-L ( Paracoccus pantotrophus )
3-carboxy-2-hydroxymuconate semialdehyde decarboxylase : dhbB ( Pseudomonas reinekei )
pyruvate decarboxylase 3 : PDC6 ( Saccharomyces cerevisiae )
pyruvate decarboxylase 2 : PDC5 ( Saccharomyces cerevisiae )
pyruvate decarboxylase 1 : PDC1 ( Saccharomyces cerevisiae )
aclacinomycin 10-hydroxylase : rdmB ( Streptomyces purpurascens )
methylketone synthase 1 : MKS1 ( Lycopersicon hirsutum glabratum )
5-chloro-4-hydroxy-2-oxopentanoate decarboxylase (acylating) : salQ ( Salinispora tropica )
carboxyspermidine decarboxylase : C8J_1418 ( Campylobacter jejuni jejuni 81116 )
carboxynorspermidine decarboxylase : VVI_3048 ( Vibrio vulnificus CMCP6 )
carboxynorspermidine decarboxylase : nspC ( Vibrio alginolyticus NBRC 15630 = ATCC 17749 )
2-oxo-3-hexenedioate decarboxylase / 2-oxopent-5-chloro-3-enoate decarboxylase : cnbF ( Comamonas testosteroni CNB-1 )


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC14B.