Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc EC 1.2.1 -- With NAD(+) or NADP(+) as acceptor

Parent Class: EC-Numbers 1 -- Oxidoreductases 1.2 -- Acting on the aldehyde or oxo group of donors

Instances:
1.2.1.2 -- formate dehydrogenase ,
1.2.1.3 -- aldehyde dehydrogenase (NAD+) ,
1.2.1.4 -- aldehyde dehydrogenase (NADP+) ,
1.2.1.5 -- aldehyde dehydrogenase [NAD(P)+] ,
1.2.1.7 -- benzaldehyde dehydrogenase (NADP+) ,
1.2.1.8 -- betaine-aldehyde dehydrogenase ,
1.2.1.9 -- glyceraldehyde-3-phosphate dehydrogenase (NADP+) ,
1.2.1.10 -- acetaldehyde dehydrogenase (acetylating) ,
1.2.1.11 -- aspartate-semialdehyde dehydrogenase ,
1.2.1.12 -- glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) ,
1.2.1.13 -- glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) ,
1.2.1.15 -- malonate-semialdehyde dehydrogenase ,
1.2.1.17 -- glyoxylate dehydrogenase (acylating) ,
1.2.1.18 -- malonate-semialdehyde dehydrogenase (acetylating) ,
1.2.1.19 -- aminobutyraldehyde dehydrogenase ,
1.2.1.20 -- glutarate-semialdehyde dehydrogenase ,
1.2.1.21 -- glycolaldehyde dehydrogenase ,
1.2.1.22 -- lactaldehyde dehydrogenase ,
1.2.1.23 -- 2-oxoaldehyde dehydrogenase (NAD+) ,
1.2.1.24 -- succinate-semialdehyde dehydrogenase (NAD+) ,
1.2.1.25 -- 2-oxoisovalerate dehydrogenase (acylating) ,
1.2.1.26 -- 2,5-dioxovalerate dehydrogenase ,
1.2.1.27 -- methylmalonate-semialdehyde dehydrogenase (CoA-acylating) ,
1.2.1.28 -- benzaldehyde dehydrogenase (NAD+) ,
1.2.1.29 -- aryl-aldehyde dehydrogenase ,
1.2.1.30 -- aryl-aldehyde dehydrogenase (NADP+) ,
1.2.1.31 -- L-aminoadipate-semialdehyde dehydrogenase ,
1.2.1.32 -- aminomuconate-semialdehyde dehydrogenase ,
1.2.1.33 -- (R)-dehydropantoate dehydrogenase ,
1.2.1.36 -- retinal dehydrogenase ,
1.2.1.38 -- N-acetyl-γ-glutamyl-phosphate reductase ,
1.2.1.39 -- phenylacetaldehyde dehydrogenase ,
1.2.1.41 -- glutamate-5-semialdehyde dehydrogenase ,
1.2.1.42 -- hexadecanal dehydrogenase (acylating) ,
1.2.1.43 -- formate dehydrogenase (NADP+) ,
1.2.1.44 -- cinnamoyl-CoA reductase ,
1.2.1.46 -- formaldehyde dehydrogenase ,
1.2.1.47 -- 4-trimethylammoniobutyraldehyde dehydrogenase ,
1.2.1.48 -- long-chain-aldehyde dehydrogenase ,
1.2.1.49 -- 2-oxoaldehyde dehydrogenase (NADP+) ,
1.2.1.50 -- long-chain-fatty-acyl-CoA reductase ,
1.2.1.51 -- pyruvate dehydrogenase (NADP+) ,
1.2.1.52 -- oxoglutarate dehydrogenase (NADP+) ,
1.2.1.53 -- 4-hydroxyphenylacetaldehyde dehydrogenase ,
1.2.1.54 -- γ-guanidinobutyraldehyde dehydrogenase ,
1.2.1.57 -- butanal dehydrogenase ,
1.2.1.58 -- phenylglyoxylate dehydrogenase (acylating) ,
1.2.1.59 -- glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) ,
1.2.1.60 -- 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase ,
1.2.1.61 -- 4-hydroxymuconic-semialdehyde dehydrogenase ,
1.2.1.62 -- 4-formylbenzenesulfonate dehydrogenase ,
1.2.1.63 -- 6-oxohexanoate dehydrogenase ,
1.2.1.64 -- 4-hydroxybenzaldehyde dehydrogenase ,
1.2.1.65 -- salicylaldehyde dehydrogenase ,
1.2.1.67 -- vanillin dehydrogenase ,
1.2.1.68 -- coniferyl-aldehyde dehydrogenase ,
1.2.1.69 -- fluoroacetaldehyde dehydrogenase ,
1.2.1.70 -- glutamyl-tRNA reductase ,
1.2.1.71 -- succinylglutamate-semialdehyde dehydrogenase ,
1.2.1.72 -- erythrose-4-phosphate dehydrogenase ,
1.2.1.73 -- sulfoacetaldehyde dehydrogenase ,
1.2.1.74 -- abieta-7,13-dien-18-al dehydrogenase ,
1.2.1.75 -- malonyl-CoA reductase (malonate semialdehyde-forming) ,
1.2.1.76 -- succinate-semialdehyde dehydrogenase (acylating) ,
1.2.1.77 -- 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) ,
1.2.1.78 -- 2-formylbenzoate dehydrogenase ,
1.2.1.79 -- succinate-semialdehyde dehydrogenase (NADP+) ,
1.2.1.80 -- long-chain acyl-[acyl-carrier-protein] reductase ,
1.2.1.81 -- sulfoacetaldehyde dehydrogenase (acylating) ,
1.2.1.82 -- β-apo-4′-carotenal oxygenase ,
1.2.1.83 -- 3-succinoylsemialdehyde-pyridine dehydrogenase ,
1.2.1.84 -- alcohol-forming fatty acyl-CoA reductase ,
1.2.1.85 -- 2-hydroxymuconate-6-semialdehyde dehydrogenase ,
1.2.1.86 -- geranial dehydrogenase ,
1.2.1.87 -- propanal dehydrogenase (CoA-propanoylating) ,
1.2.1.88 -- L-glutamate γ-semialdehyde dehydrogenase ,
1.2.1.89 -- D-glyceraldehyde dehydrogenase (NADP+) ,
1.2.1.v -- glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

Unofficial Reactions:
malonate semialdehyde + coenzyme A + NADP+ = acetyl-CoA + CO2 + NADPH ,
1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+ ,
chloroacetaldehyde + NAD+ + H2O ↔ chloroacetate + NADH + 2 H+ ,
(S)-2-amino-6-oxohexanoate + NAD+ + H2O = L-2-aminoadipate + NADH + 2 H+ ,
4-carboxybenzaldehyde + NAD+ + H2O ↔ terephthalate + NADH + 2 H+ ,
apo-4'-lycopenal + NAD(P)+ + H2O → apo-4'-lycopenoate + NADPH + H+ ,
22-oxo-docosanoate + NADP+ + H2O → docosanedioate + NADPH + 2 H+ ,
(S)-lactaldehyde + NADP+ + H2O → (S)-lactate + NADPH + 2 H+ ,
3-aminopropanal + NAD+ + H2O = β-alanine + NADH + 2 H+ ,
phosphonoacetaldehyde + NAD+ + H2O → phosphonoacetate + NADH + 2 H+ ,
hexanal + coenzyme A + NAD(P)+ ← hexanoyl-CoA + NAD(P)H + H+ ,
3-oxo-24-ethyl-26-al-cholest-4-ene + NAD+ + H2O → 3-oxo-24-ethyl-cholest-4-en-26-oate + NADH + 2 H+ ,
3-oxocholest-4-en-26-al + NAD+ + H2O → 3-oxocholest-4-en-26-oate + NADH + 2 H+ ,
a long-chain aldehyde + coenzyme A + NAD+ ← a long-chain acyl-CoA + NADH + H+ ,
(15Z)-tetracos-15-enal + coenzyme A + NAD+ ← (Z)-15-tetracosenoyl-CoA + NADH + H+ ,
a long-chain aldehyde + NADH + H+ → a long-chain alcohol + NAD+ ,
4-hydroxybenzaldehyde + NAD(P)+ + H2O → 4-hydroxybenzoate + NAD(P)H + 2 H+ ,
4-aminobutanal + NADP+ + H2O = 4-aminobutanoate + NADPH + 2 H+ ,
L-4-hydroxyglutamate semialdehyde + NAD+ + H2O → erythro-4-hydroxy-L-glutamate + NADH + 2 H+ ,
glycolaldehyde + an oxidized electron acceptor → glycolate + a reduced electron acceptor + H+ ,
(10E,12Z)-10,12-hexadecadienoate + 2 NADPH + 3 H+ → bombykol + 2 NADP+ + H2O ,
gentisaldehyde + NADP+ + H2O → gentisate + NADPH + 2 H+ ,
4-guanidinobutyraldehyde + an oxidized electron acceptor + H2O → 4-guanidinobutyrate + a reduced electron acceptor + H+ ,
18-oxo-oleate + NADP+ + H2O → α,ω-9Z-octadecenedioate + NADPH + 2 H+ ,
malonate semialdehyde + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH ,
an ω-oxo fatty acid + NAD+ + H2O → an α,ω-dicarboxylate + NADH + H+ ,
a [LysW]-C-terminal-L-glutamyl-γ-L-2-aminoadipate 6-phosphate + NADPH + H+ → a [LysW]-C-terminal-L-glutamyl-γ-L-2-aminoadipate semialdehyde + NADP+ + phosphate ,
indole-3-glycol aldehyde + an oxidized electron acceptor + H2O → indole-3-glycolate + a reduced electron acceptor + H+ ,
indole-3-glyoxal + an oxidized electron acceptor + H2O → indole-3-glyoxylate + a reduced electron acceptor + H+ ,
3-aminopropanal + NAD(P)+ + H2O → β-alanine + NAD(P)H + 2 H+ ,
sinapaldehyde + NADP+ + H2O → sinapate + NADPH + 2 H+ ,
(S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD+ + 2 H2O → L-2-aminoadipate + NADH + H+ ,
glutarate semialdehyde + NADP+ + H2O → glutarate + NADPH + 2 H+ ,
bixin aldehyde + NAD+ + oxygen → norbixin + NADH + H+ ,
2,5-dioxopentanoate + NAD(P)+ + H2O → 2-oxoglutarate + NAD(P)H + 2 H+ ,
16-oxo-palmitate + NADP+ + H2O → hexadecanedioate + NADPH + 2 H+ ,
4-(γ-glutamylamino)butanal + NAD(P)+ + H2O → 4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ ,
3-hydroxypropionaldehyde + NAD+ + H2O → 3-hydroxypropanoate + NADH + 2 H+ ,
a very long chain alcohol + coenzyme A + 2 NADP+ ← a very long chain fatty acyl-CoA + 2 NADPH + 2 H+ ,
(S)-3-methyl-2-oxopentanoate + coenzyme A + NAD+ ↔ 2-methylbutanoyl-CoA + CO2 + NADH ,
4-methyl-2-oxopentanoate + coenzyme A + NAD+ → isovaleryl-CoA + CO2 + NADH ,
pyruvate + coenzyme A + NAD+ ↔ acetyl-CoA + CO2 + NADH

Enzymes and Genes:
pyruvate dehydrogenase : aceE , aceF , lpd ( Escherichia coli K-12 substr. MG1655 )
pyruvate dehydrogenase complex : pdhB , Synpcc7942_1944 , pdhC , pdhD ( Synechococcus elongatus PCC 7942 )
pyruvate dehydrogenase complex : DLD , AF123459 , DLAT , PDHA1 , PDHB ( Ascaris suum )
pyruvate dehydrogenase complex : PDHA1 , PDHB , DLAT , PDHX , DLD ( Homo sapiens )
pyruvate dehydrogenase complex ( Crithidia fasciculata )
pyruvate dehydrogenase complex ( Pisum sativum )
pyruvate dehydrogenase complex : pdhB , pdhA , pdhC , pdhD ( Mycoplasma pneumoniae M129 )
branched-chain α-keto acid dehydrogenase complex : BCKDHB , BCKDHA , DBT , DLD ( Homo sapiens )
branched-chain α-keto acid dehydrogenase complex : bfmBAB , bfmBAA , bfmBB , pdhD ( Bacillus subtilis )
alcohol-forming fatty acyl-CoA reductase : CER4 ( Arabidopsis thaliana col )
γ-glutamyl-γ-aminobutyraldehyde dehydrogenase : puuC ( Escherichia coli K-12 substr. MG1655 )
2-ketoglutarate semialdehyde dehydrogenase : PA2217 ( Pseudomonas aeruginosa PAO1 )
α-ketoglutaric semialdehyde dehydrogenase : araE ( Azospirillum brasilense )
bixin aldehyde dehydrogenase : BADH ( Bixa orellana )
glutarate semialdehyde dehydrogenase : PA0265 ( Pseudomonas aeruginosa )
glutarate semialdehyde dehydrogenase : davD ( Pseudomonas putida )
α aminoadipate reductase : LYS2 ( Saccharomyces cerevisiae )
hydroxycinnamaldehyde dehydrogenase : REF1 ( Arabidopsis thaliana col )
[LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase : lysY ( Sulfolobus acidocaldarius )
[LysW]-L-2-aminoadipate 6-phosphate reductase : lysY ( Thermus thermophilus )
(methyl)malonate-semialdehyde dehydrogenase : mmsA ( Bacillus subtilis subtilis 168 )
malonate-semialdehyde dehydrogenase ( Enterobacter aerogenes )
malonate semialdehyde dehydrogenase ( Pseudomonas fluorescens )
malonate semialdehyde dehydrogenase ( Rattus norvegicus )
pheromone gland-specific fatty-acyl reductase : FAR ( Bombyx mori )
glycolaldehyde oxidoreductase : SSO2637 , SSO2636 , SSO2639 ( Sulfolobus solfataricus P2 )
Δ1-pyrroline-5-carboxylate dehydrogenase, mitochondrial : ALDH4A1 ( Homo sapiens )
Δ1-pyrroline-5-carboxylate dehydrogenase ( Bos taurus )
acyl-CoA reductase (NADH) : U80676 ( Botryococcus braunii BOT88-2 )
cholest-4-en-3-one 26-monooxygenase : cyp125 ( Mycobacterium tuberculosis )
cholest-4-en-3-one 26-monooxygenase : cyp125 ( Rhodococcus jostii RHA1 )
aldehyde/alcohol dehydrogenase : adhE2 ( Clostridium acetobutylicum )
phosphonoacetaldehyde dehydrogenase : phnY ( Sinorhizobium meliloti 1021 )
betaine aldehyde / aminoaldehyde dehydrogenase : ALDH10A9 ( Arabidopsis thaliana col )
3-aminopropionaldehyde dehydrogenase ( Setaria italica )
aminopropionaldehyde dehydrogenase ( Arthrobacter sp. TMP-1 )
aldehyde dehydrogenase : ALD2 ( Saccharomyces cerevisiae )
aldehyde dehydrogenase : ALD3 ( Saccharomyces cerevisiae )
NAD(P)+ L-lactaldehyde dehydrogenase : LADH ( Scheffersomyces stipitis CBS 6054 )
aldehyde dehydrogenase, mitochondrial : ALD5 ( Saccharomyces cerevisiae )
potassium-activated aldehyde dehydrogenase, mitochondrial : ALD4 ( Saccharomyces cerevisiae )
NADPH-dependent aldehyde reductase : yqhD ( Escherichia coli K-12 substr. MG1655 )
apo-4'-lycopenal dehydrogenase : YLO-1 ( Neurospora crassa )
4-carboxybenzaldehyde dehydrogenase / 4-sulfobenzaldehyde dehydrogenase : tsaD ( Comamonas testosteroni T-2 )
Δ1-piperideine-6-carboxylate dehydrogenase : pcd ( [Flavobacterium] lutescens )
Δ1-piperideine-6-carboxylate dehydrogenase : pcd ( Streptomyces clavuligerus )
L-α-aminoadipate δ-semialdehyde:NAD oxidoreductase : amaA ( Pseudomonas putida )
α-aminoadipic semialdehyde dehydrogenase : ALDH7A1 ( Homo sapiens )
chloroacetaldehyde dehydrogenase ( Xanthobacter autotrophicus )
malonate-semialdehyde dehydrogenase (acetylating) : dddC ( Halomonas sp. HTNK1 )


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC14B.