|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Transport Reactions → Transport Reactions of Unknown Mechanism|
|Reactions Classified By Substrate → Small-Molecule Reactions|
Reaction Locations: inner membrane (sensu Gram-negative Bacteria)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Phosphorylation of hydroxymethylpyrimidine (HMP) by HMP kinase is the first step in a non-essential salvage reaction of the superpathway of thiamin diphosphate biosynthesis I pathway. This pathway is common to both E.coli and S. typhimurium and has been extensively studied in both organisms. Salvage of HMP from the culture medium has been experimentally demonstrated in S. typhimurium [Bellion83].
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