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Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Reaction: 3.1.1.32

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.1.1.32

Enzymes and Genes:
outer membrane phospholipase Inferred from experiment : pldA

Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.

Reaction Locations: periplasmic space (sensu Gram-negative Bacteria)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phospholipase A1

Summary:
HAS A MUCH BROADER SPECIFICITY THAN EC 3.1.1.4.

Enzyme Commission Summary:
This enzyme has a much broader specificity than EC 3.1.1.4 phospholipase A2. Requires Ca2+.

Citations: [Gatt68, Scandella71, vandenBosch80, vandenBosch74]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.1.1.32 , ENZYME:EC:3.1.1.32 , IUBMB-ExplorEnz:EC:3.1.1.32

Credits:
Created 17-Jan-2012 by Keseler I , SRI International


References

Gatt68: Gatt S (1968). "Purification and properties of phospholipase A-1 from rat and calf brain." Biochim Biophys Acta 159(2);304-16. PMID: 5657461

Scandella71: Scandella CJ, Kornberg A (1971). "A membrane-bound phospholipase A1 purified from Escherichia coli." Biochemistry 10(24);4447-56. PMID: 4946924

vandenBosch74: van den Bosch H, Aarsman AJ, van Deenen LL (1974). "Isolation and properties of a phospholipase A1 activity from beef pancreas." Biochim Biophys Acta 348(2);197-209. PMID: 4858811

vandenBosch80: van den Bosch H (1980). "Intracellular phospholipases A." Biochim Biophys Acta 604(2);191-246. PMID: 6252969


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, biocyc14.