Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 3.1.27.6

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions

EC Number: 3.1.27.6

Enzymes and Genes:
RNase I, cleaves phosphodiester bond between any two nucleotides Inferred from experiment : rna

Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number, which can be found here and here .

Reaction Locations: periplasmic space (sensu Gram-negative Bacteria)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: Enterobacter ribonuclease

Enzyme Commission Summary:
Preference for cleavage at CpA. Homopolymers of A, U or G are not hydrolysed.

Citations: [Spahr61, Levy70, Marotta73]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.1.27.6 , ENZYME:EC:3.1.27.6 , IUBMB-ExplorEnz:EC:3.1.27.6

Credits:
Created 20-Aug-2010 by Shearer A , SRI International


References

Levy70: Levy CC, Goldman P (1970). "Residue specificity of a ribonuclease which hydrolyzes polycytidylic acid." J Biol Chem 245(12);3257-62. PMID: 5432809

Marotta73: Marotta CA, Levy CC, Weissman SM, Varricchio F (1973). "Preferred sites of digestion of a ribonuclease from Enterobacter sp. in the sequence analysis of Bacillus stearothermophilus 5S ribonucleic acid." Biochemistry 12(15);2901-4. PMID: 4719125

Spahr61: Spahr PF, Hollingworth BR (1961). "Purification and Mechanism of Action of Ribonuclease from Escherichia coli Ribosomes." J Biol Chem 236: 823-31.


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, BIOCYC14B.