Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 2.7.7.56

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions tRNA-Reactions

EC Number: 2.7.7.56

Enzymes and Genes:
RNase PH Inferred from experiment : rph

In Pathway: tRNA processing

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: tRNA nucleotidyltransferase

Enzyme Commission Synonyms: phosphate-dependent exonuclease, RNase PH, ribonuclease PH

Enzyme Commission Summary:
Brings about the final exonucleolytic trimming of the 3-terminus of tRNA precursors in Escherichia coli by a phosphorolysis, producing a mature 3-terminus on tRNA and nucleoside diphosphate. Not identical with EC 2.7.7.8 polyribonucleotide nucleotidyltransferase.

Citations: [Cudny88, Deutscher88]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.7.56 , ENZYME:EC:2.7.7.56 , IUBMB-ExplorEnz:EC:2.7.7.56

Credits:
Created 16-Jun-2010 by Shearer A , SRI International


References

Cudny88: Cudny H, Deutscher MP (1988). "3' processing of tRNA precursors in ribonuclease-deficient Escherichia coli. Development and characterization of an in vitro processing system and evidence for a phosphate requirement." J Biol Chem 263(3);1518-23. PMID: 3275667

Deutscher88: Deutscher MP, Marshall GT, Cudny H (1988). "RNase PH: an Escherichia coli phosphate-dependent nuclease distinct from polynucleotide phosphorylase." Proc Natl Acad Sci U S A 85(13);4710-4. PMID: 2455297


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13B.