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Escherichia coli K-12 substr. MG1655 Reaction: 3.5.1.28

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.1.28

Enzymes and Genes:
anhydro-N-acetylmuramoyl-L-alanine amidase Inferred from experiment Inferred by computational analysis : amiD
N-acetyl-anhydromuramyl-L-alanine-amidase : ampD

In Pathway: anhydromuropeptides recycling

Supersedes EC numbers: 3.4.19.10, 3.4.17.7, 3.4.12.5

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: N-acetylmuramoyl-L-alanine amidase

Enzyme Commission Synonyms: acetylmuramyl-L-alanine amidase, N-acetylmuramyl-L-alanine amidase, N-acylmuramyl-L-alanine amidase, acetylmuramoyl-alanine amidase, N-acetylmuramic acid L-alanine amidase, acetylmuramyl-alanine amidase, N-acetylmuramylalanine amidase, murein hydrolase, N-acetylmuramoyl-L-alanine amidase type I, N-acetylmuramoyl-L-alanine amidase type II

Citations: [Herbold75, Herbold75a, Ghuysen69, Ward82]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.5.1.28 , ENZYME:EC:3.5.1.28 , IUBMB-ExplorEnz:EC:3.5.1.28


References

Ghuysen69: Ghuysen JM, Dierickx L, Coyette J, Leyh-Bouille M, Guinand M, Campbell JN (1969). "An improved technique for the preparation of Streptomyces peptidases and N-acetylmuramyl-l-alanine amidase active on bacterial wall peptidoglycans." Biochemistry 8(1);213-22. PMID: 5777325

Herbold75: Herbold DR, Glaser L (1975). "Bacillus subtilis N-acetylmuramic acid L-alanine amidase." J Biol Chem 250(5);1676-82. PMID: 803507

Herbold75a: Herbold DR, Glaser L (1975). "Interaction of N-acetylmuramic acid L-alanine amidase with cell wall polymers." J Biol Chem 250(18);7231-8. PMID: 809432

Ward82: Ward JB, Curtis CA, Taylor C, Buxton RS (1982). "Purification and characterization of two phage PBSX-induced lytic enzymes of Bacillus subtilis 168: an N-acetylmuramoyl-L-alanine amidase and an N-acetylmuramidase." J Gen Microbiol 128(6);1171-8. PMID: 6126517


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Mon Mar 2, 2015, BIOCYC14B.