Escherichia coli K-12 substr. MG1655 Reaction: 2.3.1.-

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.-

Enzymes and Genes:
palmitoyl transferase for Lipid A Inferred from experiment : pagP

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 2.3.1 -- Transferring groups other than amino-acyl groups

The donor phospholipid has palmitate at the sn-1 position [Bishop00]. A PagP homodimer catalyzes palmitate transfer from a phospholipid (sn-1 position) to lipid A or to a lipid A precursor (N-linked hydroxymyristate on the proximal unit) [Bishop00].

Gene-Reaction Schematic: ?

Gene-Reaction Schematic


Bishop00: Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR (2000). "Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria." EMBO J 19(19);5071-80. PMID: 11013210

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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