Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

Enzymes and Genes:
palmitoyl transferase for Lipid A Inferred from experiment : pagP

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Marked as unbalanced.

Summary:
The donor phospholipid has palmitate at the sn-1 position [Bishop00]. A PagP homodimer catalyzes palmitate transfer from a phospholipid (sn-1 position) to lipid A or to a lipid A precursor (N-linked hydroxymyristate on the proximal unit) [Bishop00].

Gene-Reaction Schematic: ?


References

Bishop00: Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR (2000). "Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria." EMBO J 19(19);5071-80. PMID: 11013210


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC13A.