Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 3.2.1.177

Superclasses: Reactions Classified By Conversion Type Complex Processes
Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.2.1.177

Enzymes and Genes:
α-D-xyloside xylohydrolase Inferred from experiment : yicI

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: α-D-xyloside xylohydrolase

Enzyme Commission Synonyms: α-xylosidase

Enzyme Commission Summary:
The enzyme catalyses hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide. Representative α-xylosidases from glycoside hydrolase family 31 utilize a two-step (double-displacement) mechanism involving a covalent glycosyl-enzyme intermediate, and retain the anomeric configuration of the product.

Citations: [Moracci00, Sampedro01, Crombie02, Lovering05, Iglesias06, Okuyama06, Larsbrink11]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.2.1.177 , ENZYME:EC:3.2.1.177 , IUBMB-ExplorEnz:EC:3.2.1.177

Credits:
Created 13-May-2011 by Caspi R , SRI International


References

Crombie02: Crombie HJ, Chengappa S, Jarman C, Sidebottom C, Reid JS (2002). "Molecular characterisation of a xyloglucan oligosaccharide-acting alpha-D-xylosidase from nasturtium (Tropaeolum majus L.) cotyledons that resembles plant 'apoplastic' alpha-D-glucosidases." Planta 214(3);406-13. PMID: 11859845

Iglesias06: Iglesias N, Abelenda JA, Rodino M, Sampedro J, Revilla G, Zarra I (2006). "Apoplastic glycosidases active against xyloglucan oligosaccharides of Arabidopsis thaliana." Plant Cell Physiol 47(1);55-63. PMID: 16267099

Larsbrink11: Larsbrink J, Izumi A, Ibatullin FM, Nakhai A, Gilbert HJ, Davies GJ, Brumer H (2011). "Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification." Biochem J 436(3);567-80. PMID: 21426303

Lovering05: Lovering AL, Lee SS, Kim YW, Withers SG, Strynadka NC (2005). "Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate." J Biol Chem 280(3);2105-15. PMID: 15501829

Moracci00: Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M (2000). "Identification and molecular characterization of the first alpha -xylosidase from an archaeon." J Biol Chem 275(29);22082-9. PMID: 10801892

Okuyama06: Okuyama M, Kaneko A, Mori H, Chiba S, Kimura A (2006). "Structural elements to convert Escherichia coli alpha-xylosidase (YicI) into alpha-glucosidase." FEBS Lett 580(11);2707-11. PMID: 16631751

Sampedro01: Sampedro J, Sieiro C, Revilla G, Gonzalez-Villa T, Zarra I (2001). "Cloning and expression pattern of a gene encoding an alpha-xylosidase active against xyloglucan oligosaccharides from Arabidopsis." Plant Physiol 126(2);910-20. PMID: 11402218


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, biocyc14.