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Escherichia coli K-12 substr. MG1655 Reaction: 1.14.13.127


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.14.13.127

Enzymes and Genes:
3-(3-hydroxyphenyl)propionate 2-hydroxylaseInferred from experiment: mhpA

In Pathway: cinnamate and 3-hydroxycinnamate degradation to 2-oxopent-4-enoate

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3-(3-hydroxyphenyl)propanoate hydroxylase

Enzyme Commission Synonyms: mhpA (gene name)

Enzyme Commission Summary:
A flavoprotein (FAD). This enzyme participates in a meta-cleavage pathway employed by the bacterium Escherichia coli for the degradation of various phenylpropanoid compounds.

Citations: [Burlingame83 , Burlingame86, Ferrandez97a, Diaz98]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:1.14.13.127, ENZYME:EC:1.14.13.127, IUBMB-ExplorEnz:EC:1.14.13.127


References

Burlingame83: Burlingame R, Chapman PJ (1983). "Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli." J Bacteriol 1983;155(1);113-21. PMID: 6345502

Burlingame86: Burlingame RP, Wyman L, Chapman PJ (1986). "Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation." J Bacteriol 1986;168(1);55-64. PMID: 3531186

Diaz98: Diaz E, Ferrandez A, Garcia JL (1998). "Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12." J Bacteriol 1998;180(11);2915-23. PMID: 9603882

Ferrandez97a: Ferrandez A, Garcia JL, Diaz E (1997). "Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12." J Bacteriol 1997;179(8);2573-81. PMID: 9098055


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.5 on Sun May 1, 2016, BIOCYC11A.