Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
hydroxymethylpyrimidine kinase Inferred from experiment : thiD
hydroxymethylpyrimidine kinase Inferred from experiment : pdxK

In Pathway: hydroxymethylpyrimidine salvage

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: hydroxymethylpyrimidine kinase

Enzyme Commission Synonyms: hydroxymethylpyrimidine kinase (phosphorylating)

This reaction is involved in two biosynthetic pathways. It is one of the first steps in the biosynthesis of thiamine pyrophosphate and it is a reaction in the second part of the multistep synthesis of the pyrimidine moiety of thiamine.

Enzyme Commission Summary:
CTP, UTP and GTP can act as donors.

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc14.