Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 2.7.1.49

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.49

Enzymes and Genes:
hydroxymethylpyrimidine kinase Inferred from experiment : thiD
hydroxymethylpyrimidine kinase Inferred from experiment : pdxK

In Pathway: hydroxymethylpyrimidine salvage

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: hydroxymethylpyrimidine kinase

Enzyme Commission Synonyms: hydroxymethylpyrimidine kinase (phosphorylating)

Summary:
This reaction is involved in two biosynthetic pathways. It is one of the first steps in the biosynthesis of thiamine pyrophosphate and it is a reaction in the second part of the multistep synthesis of the pyrimidine moiety of thiamine.

Enzyme Commission Summary:
CTP, UTP and GTP can act as donors.

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.1.49 , ENZYME:EC:2.7.1.49 , IUBMB-ExplorEnz:EC:2.7.1.49


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Tue Nov 25, 2014, biocyc13.