|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
In this reaction nitrate/nitrite response regulator NarP is phosphorylated by phospho-NarQ sensor protein.
In the presence of both nitrate and nitrite the nitrate/nitrite response regulator NarP can be phosphorylated by both nitrate/nitrite sensor kinase-phosphotransferases phospho-NarX and phospho-NarQ. In this activated state phospho-NarP can act as an activator of transcription of the fdnG operon and nitrate or nitrite reductase systems and repressor of expression of genes for other anaerobic systems. [Hoch95, Rabin93]
Rabin93: Rabin RS, Stewart V (1993). "Dual response regulators (NarL and NarP) interact with dual sensors (NarX and NarQ) to control nitrate- and nitrite-regulated gene expression in Escherichia coli K-12." J Bacteriol 1993;175(11);3259-68. PMID: 8501030
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