Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
alkaline phosphataseInferred from experiment: phoA
histidinol-phosphataseInferred from experiment: hisB

In Pathway: L-histidine biosynthesis

Reaction Locations: periplasm (sensu Gram-negative Bacteria), cytosol

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: histidinol-phosphatase

Enzyme Commission Synonyms: histidinol phosphate phosphatase, L-histidinol phosphate phosphatase, histidinolphosphate phosphatase, HPpase, histidinolphosphatase

This is the ninth step of the histidine biosynthesis pathway

Citations: [AMES57]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


AMES57: AMES BN (1957). "The biosynthesis of histidine; L-histidinol phosphate phosphatase." J Biol Chem 226(2);583-93. PMID: 13438843

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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