Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 1.2.1.41

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.2.1.41

Enzymes and Genes:
glutamate-5-semialdehyde dehydrogenase Inferred from experiment : proA

In Pathway: proline biosynthesis I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glutamate-5-semialdehyde dehydrogenase

Enzyme Commission Synonyms: γ-glutamyl phosphate reductase, β-glutamylphosphate reductase, glutamate semialdehyde dehydrogenase, glutamate-γ-semialdehyde dehydrogenase

Enzyme Commission Summary:
This is the second step in the proline biosynthesis pathway.

Citations: [Baich71]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:1.2.1.41 , ENZYME:EC:1.2.1.41 , IUBMB-ExplorEnz:EC:1.2.1.41


References

Baich71: Baich A (1971). "The biosynthesis of proline in Escherichia coli: phosphate-dependent glutamate -semialdehyde dehydrogenase (NADP), the second enzyme in the pathway." Biochim Biophys Acta 244(1);129-34. PMID: 4399189


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.