Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
glutamate-5-semialdehyde dehydrogenaseInferred from experiment: proA

In Pathway: L-proline biosynthesis I

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glutamate-5-semialdehyde dehydrogenase

Enzyme Commission Synonyms: γ-glutamyl phosphate reductase, β-glutamylphosphate reductase, glutamate semialdehyde dehydrogenase, glutamate-γ-semialdehyde dehydrogenase

Enzyme Commission Summary:
This is the second step in the proline biosynthesis pathway.

Citations: [Baich71]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Baich71: Baich A (1971). "The biosynthesis of proline in Escherichia coli: phosphate-dependent glutamate -semialdehyde dehydrogenase (NADP), the second enzyme in the pathway." Biochim Biophys Acta 244(1);129-34. PMID: 4399189

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.5 on Sat Nov 28, 2015, BIOCYC11A.