|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
EC Number: 18.104.22.168
22.214.171.124: citrate → acetate + oxaloacetate
Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: citrate CoA-transferase
This is the first reaction in the two-step sequence of citrate lyase. The citryl-ACP intermediate is formed by transfer of ACP from acetyl-ACP.
Enzyme Commission Summary:
The enzyme is a component of EC 126.96.36.199 [citrate (pro-3S)-lyase]. Also catalyses the transfer of thioacyl carrier protein from its acetyl thioester to citrate.
Dimroth77: Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate." Eur J Biochem 80(2);479-88. PMID: 336371
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