|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
EC Number: 18.104.22.168
22.214.171.124: citrate → acetate + oxaloacetate
In Pathway: citrate degradation
Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: citrate CoA-transferase
This is the first reaction in the two-step sequence of citrate lyase. The citryl-ACP intermediate is formed by transfer of ACP from acetyl-ACP.
Enzyme Commission Summary:
The enzyme is a component of EC 126.96.36.199, citrate (pro-3S)-lyase. Also catalyses the transfer of thioacyl carrier protein from its acetyl thioester to citrate.
Citations: [Dimroth77 ]
Dimroth77: Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate." Eur J Biochem 80(2);479-88. PMID: 336371
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