|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
In Pathway: L-asparagine biosynthesis II
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: aspartate—ammonia ligase
Enzyme Commission Synonyms: asparagine synθse, L-asparagine synθse
This is one of two reactions in E. coli that synthesizes asparagine from aspartate. The other reaction uses glutamine as the preferred nitrogen donor.
RAVEL62: RAVEL JM, NORTON SJ, HUMPHREYS JS, SHIVE W (1962). "Asparagine biosynthesis in Lactobacillus arabinosus and its control by asparagine through enzyme inhibition and repression." J Biol Chem 237;2845-9. PMID: 14490631
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