Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
twitter

Escherichia coli K-12 substr. MG1655 Reaction: 4.3.2.2


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 4.3.2.2

Enzymes and Genes:
adenylosuccinate lyaseInferred from experiment: purB

In Pathway: adenosine ribonucleotides de novo biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: adenylosuccinate lyase

Enzyme Commission Synonyms: adenylosuccinase, succino AMP-lyase, 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase, 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)

Summary:
The final step in the de novo biosynthesis of purines, the second of the two step sequence from IMP to AMP.

Enzyme Commission Summary:
Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5-aminoimidazole.

Citations: [CARTER56]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:4.3.2.2, ENZYME:EC:4.3.2.2, IUBMB-ExplorEnz:EC:4.3.2.2


References

CARTER56: CARTER CE, COHEN LH (1956). "The preparation and properties of adenylosuccinase and adenylosuccinic acid." J Biol Chem 222(1);17-30. PMID: 13366975


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed May 4, 2016, biocyc14.