|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
Enzymes and Genes:
acid phosphatase / phosphotransferase: aphA
UMP phosphatase: umpH
pyrimidine nucleotidase: yjjG
broad specificity 5'(3')-nucleotidase and polyphosphatase: umpG
Reaction Locations: periplasm (sensu Gram-negative Bacteria), cytosol
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
AMP + H2O → adenosine + phosphate (188.8.131.52)
IMP + H2O → inosine + phosphate (184.108.40.206/3.1.3.-)
GMP + H2O → guanosine + phosphate (220.127.116.11)
UMP + H2O → uridine + phosphate (18.104.22.168)
CMP + H2O → cytidine + phosphate (22.214.171.124/126.96.36.199)
Enzyme Commission Primary Name: 5′-nucleotidase
Enzyme Commission Synonyms: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase
This reaction is involved in the hydrolysis of nucleotides.
Enzyme Commission Summary:
Wide specificity for 5-nucleotides.
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493