|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 184.108.40.206
Enzymes and Genes:
acid phosphatase / phosphotransferase: aphA
UMP phosphatase: umpH
pyrimidine nucleotidase: yjjG
broad specificity 5'(3')-nucleotidase and polyphosphatase: umpG
Reaction Locations: periplasm (sensu Gram-negative Bacteria), cytosol
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
UMP + H2O → uridine + phosphate (220.127.116.11)
CMP + H2O → cytidine + phosphate (18.104.22.168/22.214.171.124)
AMP + H2O → adenosine + phosphate (126.96.36.199)
IMP + H2O → inosine + phosphate (188.8.131.52/3.1.3.-)
GMP + H2O → guanosine + phosphate (184.108.40.206)
Enzyme Commission Primary Name: 5′-nucleotidase
Enzyme Commission Synonyms: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase
This reaction is involved in the hydrolysis of nucleotides.
Enzyme Commission Summary:
Wide specificity for 5-nucleotides.
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