|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
Supersedes EC number: 18.104.22.168
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Marked as unbalanced.
Enzyme Commission Primary Name: oligonucleotidase
Enzyme Commission Synonyms: oligoribonuclease
from the IUBMB Enzyme Nomenclature web site: "Exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates. Also hydrolyses NAD+ to NMN and AMP. Formerly EC 22.214.171.124."
Enzyme Commission Summary:
This enzyme catalyzes exonucleolytic cleavage of oligonucleotides to yield nucleoside 5-phosphates.
Also hydrolyses NAD+ to NMN and AMP.
Citations: [Futai67 ]
Futai67: Futai M, Mizuno D (1967). "A new phosphodiesterase forming nucleoside 5'-monophosphate from rat liver. Its partial purification and substrate specificity for nicotinamide adenine dinucleotide and oligonucleotides." J Biol Chem 242(22);5301-7. PMID: 4294333
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