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Escherichia coli K-12 substr. MG1655 Polypeptide: biofilm-dependent modulation protein



Gene: bdm Accession Numbers: G6776 (EcoCyc), b1481, ECK1475

Synonyms: yddX, f92

Regulation Summary Diagram: ?

Summary:
bdm is a member of the Rcs regulon [Hagiwara03]. Expression of bdm is reduced within biofilms [PrigentCombaret99] and is increased under high osmolarity [Weber02], which is RcsB dependent [FrancezCharlot05]. bdm is also positively regulated by the Rcs signaling system in response to low temperature growth in glucose and to high external zinc concentrations [Hagiwara03].

bdm: "biofilm-dependent modulation" [FrancezCharlot05]

Map Position: [1,554,089 <- 1,554,304] (33.5 centisomes)
Length: 216 bp / 71 aa

Molecular Weight of Polypeptide: 7.987 kD (from nucleotide sequence)

Unification Links: ASAP:ABE-0004938 , EchoBASE:EB4048 , EcoGene:EG14301 , Ecol199310Cyc:C1914 , EcoliWiki:b1481 , OU-Microarray:b1481 , PortEco:bdm , PR:PRO_000022206 , Protein Model Portal:P76127 , RefSeq:NP_415998 , RegulonDB:G6776 , String:511145.b1481 , UniProt:P76127

Relationship Links: InterPro:IN-FAMILY:IPR019625 , Pfam:IN-FAMILY:PF10684

Genetic Regulation Schematic: ?

Gene Class: ORFs

Essentiality data for bdm knockouts: ?

Growth Medium Growth? T (°C) O2 pH Osm/L Growth Observations
LB enriched Yes 37 Aerobic 6.95   Yes [Gerdes03, Comment 1]
LB Lennox Yes 37 Aerobic 7   Yes [Baba06, Comment 2]
M9 medium with 1% glycerol Yes 37 Aerobic 7.2 0.35 Yes [Joyce06, Comment 3]
MOPS medium with 0.4% glucose Yes 37 Aerobic 7.2 0.22 Yes [Baba06, Comment 2]

Gene Local Context (not to scale): ?

Transcription Units:

Notes:

History:
Markus Krummenacker on Tue Oct 14, 1997:
Gene object created from Blattner lab Genbank (v. M52) entry.


References

Baba06: Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006). "Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection." Mol Syst Biol 2;2006.0008. PMID: 16738554

FrancezCharlot05: Francez-Charlot A, Castanie-Cornet MP, Gutierrez C, Cam K (2005). "Osmotic Regulation of the Escherichia coli bdm (Biofilm-Dependent Modulation) Gene by the RcsCDB His-Asp Phosphorelay." J Bacteriol 187(11);3873-7. PMID: 15901715

Gerdes03: Gerdes SY, Scholle MD, Campbell JW, Balazsi G, Ravasz E, Daugherty MD, Somera AL, Kyrpides NC, Anderson I, Gelfand MS, Bhattacharya A, Kapatral V, D'Souza M, Baev MV, Grechkin Y, Mseeh F, Fonstein MY, Overbeek R, Barabasi AL, Oltvai ZN, Osterman AL (2003). "Experimental determination and system level analysis of essential genes in Escherichia coli MG1655." J Bacteriol 185(19);5673-84. PMID: 13129938

Hagiwara03: Hagiwara D, Sugiura M, Oshima T, Mori H, Aiba H, Yamashino T, Mizuno T (2003). "Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli." J Bacteriol 185(19);5735-46. PMID: 13129944

Joyce06: Joyce AR, Reed JL, White A, Edwards R, Osterman A, Baba T, Mori H, Lesely SA, Palsson BO, Agarwalla S (2006). "Experimental and computational assessment of conditionally essential genes in Escherichia coli." J Bacteriol 188(23);8259-71. PMID: 17012394

PrigentCombaret99: Prigent-Combaret C, Vidal O, Dorel C, Lejeune P (1999). "Abiotic surface sensing and biofilm-dependent regulation of gene expression in Escherichia coli." J Bacteriol 181(19);5993-6002. PMID: 10498711

Weber02: Weber A, Jung K (2002). "Profiling early osmostress-dependent gene expression in Escherichia coli using DNA macroarrays." J Bacteriol 184(19);5502-7. PMID: 12218039

Other References Related to Gene Regulation

Kamenšek13: Kamenšek S, Žgur-Bertok D (2013). "Global transcriptional responses to the bacteriocin colicin M in Escherichia coli." BMC Microbiol 13;42. PMID: 23421615


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, biocyc13.