Escherichia coli K-12 substr. MG1655 Polypeptide: GlrK sensory histidine kinase - phosphorylated

Gene: glrK Accession Numbers: G7345 (EcoCyc), b2556, ECK2553

Synonyms: yfhZ, yfhK, GlrK-Phis259

Regulation Summary Diagram: ?

Regulation summary diagram for glrK

Alternative forms of GlrK sensory histidine kinase - phosphorylated: GlrK sensory histidine kinase (summary available)

This is the phosphorylated form of GlrK - the sensor histidine kinase of the GlrKR two-component signal transduction system.

Locations: inner membrane

Map Position: [2,687,693 <- 2,689,120] (57.93 centisomes, 209°)
Length: 1428 bp / 475 aa

Unification Links: ASAP:ABE-0008409 , EchoBASE:EB3234 , EcoGene:EG13214 , EcoGene:EG13461 , OU-Microarray:b2556 , PortEco:glrK , PR:PRO_000025104 , RegulonDB:G7345

In Paralogous Gene Group: 122 (29 members)

Reactions known to consume the compound:

GlrKR Two-Component Signal Transduction System :
GlrK sensory histidine kinase - phosphorylated + GlrR → GlrK + GlrR-Pasp56

Reactions known to produce the compound:

GlrKR Two-Component Signal Transduction System :
GlrK + ATP → GlrK sensory histidine kinase - phosphorylated + ADP

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

GO Terms:

Cellular Component: GO:0005886 - plasma membrane

MultiFun Terms: information transfer protein related posttranslational modification
regulation type of regulation posttranscriptional covalent modification, demodification, maturation
regulation type of regulation transcriptional level complex regulation two component regulatory systems (external signal)

Created 17-Dec-2009 by Mackie A , Macquarie University

Sequence Features

Protein sequence of GlrK sensory histidine kinase - phosphorylated with features indicated

Feature Class Location Citations Comment State
Phosphorylation-Modification 259
UniProt: Phosphohistidine; by autocatalysis; Non-Experimental Qualifier: by similarity.

Gene Local Context (not to scale): ?

Gene local context diagram

Transcription Unit:

Transcription-unit diagram


Peter D. Karp on Wed Jan 18, 2006:
Gene right-end position adjusted based on analysis performed in the 2005 E. coli annotation update [Riley06 ].
Markus Krummenacker on Tue Oct 14, 1997:
Gene object created from Blattner lab Genbank (v. M52) entry.


Riley06: Riley M, Abe T, Arnaud MB, Berlyn MK, Blattner FR, Chaudhuri RR, Glasner JD, Horiuchi T, Keseler IM, Kosuge T, Mori H, Perna NT, Plunkett G, Rudd KE, Serres MH, Thomas GH, Thomson NR, Wishart D, Wanner BL (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34(1);1-9. PMID: 16397293

UniProt13: UniProt Consortium (2013). "UniProt version 2013-08 released on 2013-08-01 00:00:00." Database.

Other References Related to Gene Regulation

Reichenbach09: Reichenbach B, Gopel Y, Gorke B (2009). "Dual control by perfectly overlapping sigma(54)- and sigma(70)-promoters adjusts small RNA GlmY expression to different environmental signals." Mol Microbiol 74(5):1054-70. PMID: 19843219

Reitzer01: Reitzer L, Schneider BL (2001). "Metabolic context and possible physiological themes of sigma(54)-dependent genes in Escherichia coli." Microbiol Mol Biol Rev 65(3);422-44, table of contents. PMID: 11528004

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 13, 2015, biocyc13.