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Escherichia coli K-12 substr. MG1655 Polypeptide: conserved protein with NAD(P)-binding Rossman fold



Gene: yqeB Accession Numbers: G7494 (EcoCyc), b2875, ECK2871

Regulation Summary Diagram: ?

Summary:
Partial phylogenetic profiling suggested that yqeB belongs to a system connected to selenium-dependent molybdenum hydroxylases [Haft08].

Locations: cytosol

Map Position: [3,010,636 <- 3,012,261] (64.89 centisomes)
Length: 1626 bp / 541 aa

Molecular Weight of Polypeptide: 57.682 kD (from nucleotide sequence)

Unification Links: ASAP:ABE-0009441 , DIP:DIP-12851N , EchoBASE:EB2870 , EcoGene:EG13058 , EcoliWiki:b2875 , OU-Microarray:b2875 , PortEco:yqeB , Protein Model Portal:Q46808 , RefSeq:NP_417351 , RegulonDB:G7494 , SMR:Q46808 , String:511145.b2875 , UniProt:Q46808

Relationship Links: InterPro:IN-FAMILY:IPR003777 , InterPro:IN-FAMILY:IPR017695 , InterPro:IN-FAMILY:IPR027051 , Pfam:IN-FAMILY:PF02625 , Pfam:IN-FAMILY:PF13478

In Paralogous Gene Group: 85 (2 members)

GO Terms:

Cellular Component: GO:0005829 - cytosol Inferred by computational analysis [DiazMejia09]

Gene Class: ORFs

Essentiality data for yqeB knockouts: ?

Growth Medium Growth? T (°C) O2 pH Osm/L Growth Observations
LB enriched Yes 37 Aerobic 6.95   Yes [Gerdes03, Comment 1]
LB Lennox Yes 37 Aerobic 7   Yes [Baba06, Comment 2]
M9 medium with 1% glycerol Yes 37 Aerobic 7.2 0.35 Yes [Joyce06, Comment 3]
MOPS medium with 0.4% glucose Yes 37 Aerobic 7.2 0.22 Yes [Baba06, Comment 2]

Credits:
Last-Curated ? 28-Jan-2014 by Keseler I , SRI International


Gene Local Context (not to scale): ?

Transcription Unit:

Notes:

History:
Peter D. Karp on Thu Jan 16, 2003:
Predicted gene function revised as a result of E. coli genome reannotation by Serres et al. [Serres01 ].
Markus Krummenacker on Tue Oct 14, 1997:
Gene object created from Blattner lab Genbank (v. M52) entry.


References

Baba06: Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006). "Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection." Mol Syst Biol 2;2006.0008. PMID: 16738554

DiazMejia09: Diaz-Mejia JJ, Babu M, Emili A (2009). "Computational and experimental approaches to chart the Escherichia coli cell-envelope-associated proteome and interactome." FEMS Microbiol Rev 33(1);66-97. PMID: 19054114

Gerdes03: Gerdes SY, Scholle MD, Campbell JW, Balazsi G, Ravasz E, Daugherty MD, Somera AL, Kyrpides NC, Anderson I, Gelfand MS, Bhattacharya A, Kapatral V, D'Souza M, Baev MV, Grechkin Y, Mseeh F, Fonstein MY, Overbeek R, Barabasi AL, Oltvai ZN, Osterman AL (2003). "Experimental determination and system level analysis of essential genes in Escherichia coli MG1655." J Bacteriol 185(19);5673-84. PMID: 13129938

Haft08: Haft DH, Self WT (2008). "Orphan SelD proteins and selenium-dependent molybdenum hydroxylases." Biol Direct 3;4. PMID: 18289380

Joyce06: Joyce AR, Reed JL, White A, Edwards R, Osterman A, Baba T, Mori H, Lesely SA, Palsson BO, Agarwalla S (2006). "Experimental and computational assessment of conditionally essential genes in Escherichia coli." J Bacteriol 188(23);8259-71. PMID: 17012394

Serres01: Serres MH, Gopal S, Nahum LA, Liang P, Gaasterland T, Riley M (2001). "A functional update of the Escherichia coli K-12 genome." Genome Biol 2(9);RESEARCH0035. PMID: 11574054


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc13.