Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

Escherichia coli K-12 substr. MG1655 Compound: methylmethanethiosulfonate

Synonyms: MMTS

Chemical Formula: C2H6O2S2

Molecular Weight: 126.19 Daltons

Monoisotopic Molecular Weight: 125.9809208168 Daltons

SMILES: CSS(C)(=O)=O

InChI: InChI=1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3

InChIKey: InChIKey=XYONNSVDNIRXKZ-UHFFFAOYSA-N

Unification Links: ChEBI:74357 , ChemSpider:17065 , HMDB:HMDB31832 , MetaboLights:MTBLC74357 , PubChem:18064

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -67.21

Enzymes inhibited by methylmethanethiosulfonate, sorted by the type of inhibition, are:

Inhibitor (Irreversible) of: pyruvate oxidase [Koland82a]

Inhibitor (Mechanism unknown) of: 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase [Schirch85] , tRNA-guanine transglycosylase [Garcia97]


References

Garcia97: Garcia GA, Chong S (1997). "Cysteine 265 is in the active site of, but is not essential for catalysis by tRNA-guanine transglycosylase (TGT) from Escherichia coli." J Protein Chem 16(1);11-7. PMID: 9055203

Koland82a: Koland JG, Gennis RB (1982). "Identification of an active site cysteine residue in Escherichia coli pyruvate oxidase." J Biol Chem 257(11);6023-7. PMID: 7042705

Schirch85: Schirch V, Hopkins S, Villar E, Angelaccio S (1985). "Serine hydroxymethyltransferase from Escherichia coli: purification and properties." J Bacteriol 1985;163(1);1-7. PMID: 3891721


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC13A.