Escherichia coli K-12 substr. MG1655 Compound: dihydroxyacetone

Synonyms: glycerone, 1,3-dihydroxyacetone, dihydroxy-acetone

Chemical Formula: C3H6O3

Molecular Weight: 90.079 Daltons

Monoisotopic Molecular Weight: 90.0316940589 Daltons

dihydroxyacetone compound structure


InChI: InChI=1S/C3H6O3/c4-1-3(6)2-5/h4-5H,1-2H2


Unification Links: CAS:96-26-4, ChEBI:16016, ChemSpider:650, DrugBank:DB01775, HMDB:HMDB01882, IAF1260:34170, KEGG:C00184, MetaboLights:MTBLC16016, NCI:24343, PubChem:670

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -106.4

Reactions known to consume the compound:

glycerol degradation V :
dihydroxyacetone + phosphoenolpyruvate → glycerone phosphate + pyruvate

Reactions known to both consume and produce the compound:

glycerol degradation V :
glycerol + NAD+dihydroxyacetone + NADH + H+

Not in pathways:
β-D-fructofuranose 6-phosphate ↔ dihydroxyacetone + D-glyceraldehyde 3-phosphate

In Transport reactions:

Enzymes inhibited by dihydroxyacetone, sorted by the type of inhibition, are:

Inhibitor (Competitive) of: N-acetyl-β-neuraminate lyase [Aisaka91], N-acetylneuraminate lyase [Aisaka91]

This compound has been characterized as an alternative substrate of the following enzymes: glycerol kinase

In Growth Media: PMA carbon source test + dihydroxyacetone


Aisaka91: Aisaka K, Igarashi A, Yamaguchi K, Uwajima T (1991). "Purification, crystallization and characterization of N-acetylneuraminate lyase from Escherichia coli." Biochem J 1991;276 ( Pt 2);541-6. PMID: 1646603

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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