Escherichia coli K-12 substr. MG1655 Compound: 8-hydroxyquinoline-5-sulfonic acid

Superclasses: an aldehyde or ketonea ketonea cyclic ketonea quinone

Chemical Formula: C9H6NO4S

Molecular Weight: 224.21 Daltons

Monoisotopic Molecular Weight: 225.0095784083 Daltons

8-hydroxyquinoline-5-sulfonic acid compound structure

SMILES: C1(=NC2(=C(C=C1)C(S(=O)(=O)[O-])=CC=C(O)2))

InChI: InChI=1S/C9H7NO4S/c11-7-3-4-8(15(12,13)14)6-2-1-5-10-9(6)7/h1-5,11H,(H,12,13,14)/p-1


Unification Links: ChemSpider:4425604, PubChem:5260546

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -99.179

Reactions known to both consume and produce the compound:

Not in pathways:
2 a quinone + NADPH + H+ ↔ 2 a semiquinone + NADP+

In Reactions of unknown directionality:

Not in pathways:
2 a quinone + NADH + H+ = 2 a semiquinone + NAD+

Enzymes inhibited by 8-hydroxyquinoline-5-sulfonic acid, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: rhamnulose-1-phosphate aldolase [Chiu75, Schwartz72]


Chiu75: Chiu TH, Evans KL, Feingold DS (1975). "L-Rhamnulose-1-phosphate aldosase." Methods Enzymol 1975;42;364-9. PMID: 237196

Schwartz72: Schwartz NB, Feingold DS (1972). "L-rhamnulose 1-phosphate aldolase from Escherichia coli. II. Characterization as a zinc metalloenzyme." Bioinorg Chem 1:233-243.

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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