Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
twitter

Escherichia coli K-12 substr. MG1655 Compound: phenylmethanesulfonyl fluoride

Synonyms: PMSF

Chemical Formula: C7H7O2FS

Molecular Weight: 174.19 Daltons

Monoisotopic Molecular Weight: 174.01507835889998 Daltons

SMILES: C(C1(C=CC=CC=1))S(=O)(F)=O

InChI: InChI=1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2

InChIKey: InChIKey=YBYRMVIVWMBXKQ-UHFFFAOYSA-N

Unification Links: ChEBI:8102 , ChemSpider:4620 , KEGG:C06747 , PubChem:4784

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -32.38

Enzymes inhibited by phenylmethanesulfonyl fluoride, sorted by the type of inhibition, are:

Inhibitor (Irreversible) of: 1-phosphofructokinase [Buschmeier85]

Inhibitor (Mechanism unknown) of: NADPH-dependent curcumin reductase [Hassaninasab11]


References

Buschmeier85: Buschmeier B, Hengstenberg W, Deutscher J (1985). "Purification and properties of 1-phosphofructokinase from Escherichia coli." FEMS Microbiol Lett 1985;29(3):231-235.

Hassaninasab11: Hassaninasab A, Hashimoto Y, Tomita-Yokotani K, Kobayashi M (2011). "Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism." Proc Natl Acad Sci U S A 108(16):6615-20. PMID: 21467222


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, BIOCYC14A.