Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

Escherichia coli K-12 substr. MG1655 Compound: (S)-4-amino-4,5-dihydro-2-thiophenecarboxylate

Synonyms: (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid, SADTA

Citations: [Fu99]

Chemical Formula: C5H7NO2S

Molecular Weight: 145.18 Daltons

Monoisotopic Molecular Weight: 145.0197491641 Daltons

SMILES: C1(SC(C(=O)[O-])=C[CH]([N+])1)

InChI: InChI=1S/C5H7NO2S/c6-3-1-4(5(7)8)9-2-3/h1,3H,2,6H2,(H,7,8)/t3-/m0/s1

InChIKey: InChIKey=UPSMRUXNZUWKMB-VKHMYHEASA-N

Unification Links: ChemSpider:18552670 , PubChem:13457809

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -72.23

Enzymes inhibited by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylate, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: aspartate transaminase [Liu07a]

Credits:
Created 14-Jan-2010 by Fulcher C , SRI International


References

Fu99: Fu M, Nikolic D, Van Breemen RB, Silverman RB (1999). "Mechanism of inactivation of γ-aminobutyric acid aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid." J. Am. Chem. Soc. 121, 7751-7759.

Liu07a: Liu D, Pozharski E, Lepore BW, Fu M, Silverman RB, Petsko GA, Ringe D (2007). "Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms"." Biochemistry 46(37);10517-27. PMID: 17713924


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC14A.