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Escherichia coli K-12 substr. MG1655 Compound: borate

Superclasses: an ion an anion

Chemical Formula: H3O3B

Monoisotopic Molecular Weight: 62.017524462599994 Daltons

SMILES: B(O)(O)O

InChI: InChI=1S/BH3O3/c2-1(3)4/h2-4H

InChIKey: InChIKey=KGBXLFKZBHKPEV-UHFFFAOYSA-N

Unification Links: ChEBI:33118 , ChemSpider:7346 , HMDB:HMDB35731 , KEGG:C12486 , PubChem:7628

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -124.5

Enzymes activated by borate, sorted by the type of activation, are:

Activator (Mechanism unknown) of: glutaminase B [Prusiner76b]

Enzymes inhibited by borate, sorted by the type of inhibition, are:

Inhibitor (Competitive) of: cyclopropane fatty acyl phospholipid synthase [Iwig05]

Inhibitor (Mechanism unknown) of: glutaminase B [Prusiner76b] , aspartate semialdehyde dehydrogenase [Helmward89, Hegeman70a]

In Growth Media: MOPS medium with 2% glycerol , MOPS medium with 2% glucose , MOPS medium with 0.4% glucose , MOPS medium base , Neidhardt EZ rich defined medium , LB enriched


References

Hegeman70a: Hegeman G, Cohen G, Morgan R "Aspartic semialdehyde dehydrogenase (Escherichia coli K12)." Methods in Enzymology 1970; 17A:708-713.

Helmward89: Helmward Z "Handbook of Enzyme Inhibitors. 2nd, revised and enlarged edition." Weinheim, Federal Republic of Germany ; New York, NY, USA , 1989.

Iwig05: Iwig DF, Uchida A, Stromberg JA, Booker SJ (2005). "The activity of Escherichia coli cyclopropane fatty acid synthase depends on the presence of bicarbonate." J Am Chem Soc 127(33);11612-3. PMID: 16104732

Prusiner76b: Prusiner S, Stadtman ER (1976). "Regulation of glutaminase B in Escherichia coli. II. Modulaltion of activity by carbosylate and borate ions." J Biol Chem 1976;251(11);3457-62. PMID: 776969


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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