Escherichia coli K-12 substr. MG1655 Compound: Ag+

Synonyms: silver

Superclasses: an iona cationan inorganic cationa monovalent inorganic cation
an ionan inorganic ionan inorganic cationa monovalent inorganic cation

Chemical Formula: Ag

Molecular Weight: 107.87 Daltons

Monoisotopic Molecular Weight: 106.905093 Daltons


InChI: InChI=1S/Ag/q+1


Unification Links: CAS:14701-21-4, ChEBI:49468, ChemSpider:94565, HMDB:HMDB02659, IAF1260:48910, PubChem:104755

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): 0.0

In Transport reactions:
Ag+[cytosol] + H+[periplasm]Ag+[extracellular space] + H+[cytosol],
Ag+[cytosol] + ATP + H2O → Ag+[periplasm] + ADP + phosphate + H+,
an ion[periplasm]an ion[extracellular space]

Enzymes inhibited by Ag+, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: fumarase A [Xu12], NADPH-dependent curcumin reductase [Hassaninasab11], glutaminase [Hartman68]


Hartman68: Hartman SC (1968). "Glutaminase of Escherichia coli. I. Purification and general catalytic properties." J Biol Chem 1968;243(5);853-63. PMID: 4966660

Hassaninasab11: Hassaninasab A, Hashimoto Y, Tomita-Yokotani K, Kobayashi M (2011). "Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism." Proc Natl Acad Sci U S A 108(16):6615-20. PMID: 21467222

Xu12: Xu FF, Imlay JA (2012). "Silver(I), mercury(II), cadmium(II), and zinc(II) target exposed enzymic iron-sulfur clusters when they toxify Escherichia coli." Appl Environ Microbiol 78(10);3614-21. PMID: 22344668

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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