|Superclasses:||a secondary metabolite|
Siderophores are small, high-affinity iron chelating compounds secreted by microorganisms. Once outside the cell, siderophores bind Fe3+ with high affinity, and the iron-siderophore complexes are imported back into the cell by active-transport mechanisms.
Siderophores are very common in pathogenic bacteria, since iron in the host organism is usually tightly bound to proteins, resulting in an extremely low concentration of free iron in the blood.
Some grasses are known to make siderophores as well. These phytosiderophores are also known as mugineic acids.
Child Classes: a carboxylate siderophore (0) , a catecholate siderophore (1) , a hydroxamate siderophore (3) , a phytosiderophore (0) , a thiazoline siderophore (0) , an Fe(II)-siderophore (0) , an Fe(III)-siderophore (5)
SMILES: [a siderophoreH]
Reactions known to consume the compound:
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