Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0051920 - peroxiredoxin activity

Synonyms: PRDX activity, Prx activity, thiol-containing-reductant:hydroperoxide oxidoreductase activity

Definition: Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.

Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:, which has a different reaction mechanism.

Parent Classes:
GO:0016209 - antioxidant activity,
GO:0016684 - oxidoreductase activity, acting on peroxide as acceptor

Child Classes:
GO:0008379 - thioredoxin peroxidase activity (3)

Term Members:
thiol peroxidase (bcp),
conserved protein (ynjA),
osmotically inducible peroxiredoxin (osmC),
alkyl hydroperoxide reductase, AhpC component

Unification Links: GO:0051920

Relationship Links: ENZYME:RELATED-TO:, MetaCyc:RELATED-TO:

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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