Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0012501 - programmed cell death

Synonyms: GO:0016244, PCD

Definition: A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.

Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children, which are descendants of GO:0034050 'host programmed cell death induced by symbiont'.

Parent Classes:
GO:0008219 - cell death

Term Members:
CP4-44 prophage; toxin of the CbtA-CbeA toxin-antitoxin system,
toxic peptide ShoB,
toxic peptide IbsE,
predicted toxic peptide IbsD,
toxic peptide IbsC,
predicted toxic peptide IbsB,
toxic peptide IbsA,
small toxic polypeptide LdrB,
small toxic polypeptide LdrC,
small toxic polypeptide LdrA

Unification Links: GO:0012501

Relationship Links: Wikipedia:RELATED-TO:Programmed_cell_death

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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