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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0010468 - regulation of gene expression

Definition: Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availabiliy of mRNA for translation and thereby regulates the rate of production of the encoded protein via translation.

Parent Classes:
GO:0060255 - regulation of macromolecule metabolic process

Part Of:
GO:0010467 - gene expression

Child Classes:
GO:0006355 - regulation of transcription, DNA-templated (432),
GO:0010608 - posttranscriptional regulation of gene expression (87),
GO:0010628 - positive regulation of gene expression (97),
GO:0010629 - negative regulation of gene expression (163),
GO:0040029 - regulation of gene expression, epigenetic (15),
GO:0043484 - regulation of RNA splicing (1),
GO:0050684 - regulation of mRNA processing (2)

Term Members:
regulator of σ70D), stationary phase protein (rsd),
regulator of RpoS (rssB),
predicted regulator (abrB),
NarL-Phosphorylated DNA-binding transcriptional dual regulator,
RNA polymerase, sigma S (sigma 38) factor (rpoS),
RNA polymerase, sigma 32 (sigma H) factor (rpoH),
RNA polymerase, sigma 28 (sigma F) factor (fliA),
RNA polymerase, sigma 70 (sigma D) factor (rpoD),
RNA polymerase-binding transcription factor DksA,
predicted flagella assembly protein (flk),
regulator of biofilm formation (bssR),
Lrp-Leucine DNA-binding transcriptional dual regulator,
XapR-xanthosine DNA-binding transcriptional activator,
haemolysin expression modulating protein (hha),
protein-(glutamine-N5) methyltransferase (prmC),
GadY small regulatory RNA

Unification Links: GO:0010468

Relationship Links: Wikipedia:RELATED-TO:Regulation_of_gene_expression

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Mon Feb 8, 2016, biocyc14.