Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0009451 - RNA modification

Synonyms: GO:0016547

Definition: The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.

The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.

Parent Classes:
GO:0016070 - RNA metabolic process,
GO:0043412 - macromolecule modification

Child Classes:
GO:0000154 - rRNA modification (32),
GO:0001510 - RNA methylation (40),
GO:0001522 - pseudouridine synthesis (14),
GO:0006400 - tRNA modification (50),
GO:0016556 - mRNA modification (1),
GO:0035513 - oxidative RNA demethylation (1),
GO:1990884 - RNA acetylation (1)

Term Members:
tRNA pseudouridine 13 synthase (truD),
23S rRNA pseudouridine 2457 synthase (rluE),
tRNA pseudouridine 55 synthase (truB),
23S rRNA pseudouridine 2605 synthase (rluB),
23S rRNA pseudouridine synthase (rluD),
23S rRNA pseudouridine 2604 synthase (rluF),
16S rRNA pseudouridine 516 synthase (rsuA),
23S rRNA pseudouridine synthase (rluC),
tRNA pseudouridine synthase I (truA),
conserved protein (ybiA),
fused diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase (ribD),
tRNA pseudouridine 65 synthase (truC),
23S rRNA and tRNA pseudouridine synthase (rluA),
ribosomal protein S12 D88 methylthiotransferase (rimO),
isopentenyl-adenosine A37 tRNA methylthiolase (miaB),
folate-binding protein (ygfZ),
ATP-dependent helicase (hrpA),
poly(A) polymerase I (pcnB)

Unification Links: GO:0009451

Relationship Links: Wikipedia:RELATED-TO:RNA_editing

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 20.0 (software by SRI International) on Fri May 6, 2016, BIOCYC12.