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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0003906 - DNA-(apurinic or apyrimidinic site) lyase activity

Synonyms: AP lyase activity, AP site-DNA 5'-phosphomonoester-lyase activity, deoxyribonuclease (apurinic or apyrimidinic) activity, DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity, endodeoxyribonuclease (apurinic or apyrimidinic) activity

Definition: Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

Parent Classes:
GO:0004520 - endodeoxyribonuclease activity ,
GO:0016835 - carbon-oxygen lyase activity

Child Classes:
GO:0000703 - oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity (3) ,
GO:0008534 - oxidized purine nucleobase lesion DNA N-glycosylase activity (1)

Term Members:
endonuclease IV (nfo) ,
exonuclease III (xthA) ,
formamidopyrimidine DNA glycosylase (mutM) ,
endonuclease VIII (nei) ,
endonuclease III (nth)

Unification Links: GO:0003906


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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