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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0003906 - DNA-(apurinic or apyrimidinic site) lyase activity

Synonyms: AP lyase activity, AP site-DNA 5'-phosphomonoester-lyase activity, deoxyribonuclease (apurinic or apyrimidinic) activity, DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity, endodeoxyribonuclease (apurinic or apyrimidinic) activity

Definition: Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

Parent Classes:
GO:0004520 - endodeoxyribonuclease activity,
GO:0016835 - carbon-oxygen lyase activity

Child Classes:
GO:0000703 - oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity (3),
GO:0008534 - oxidized purine nucleobase lesion DNA N-glycosylase activity (1)

Term Members:
endonuclease IV (nfo),
exonuclease III (xthA),
formamidopyrimidine DNA glycosylase (mutM),
endonuclease VIII (nei),
endonuclease III (nth)

Unification Links: GO:0003906

Relationship Links: ENZYME:RELATED-TO:4.2.99.18, MetaCyc:RELATED-TO:4.2.99.18-RXN, Reactome:RELATED-TO:REACT_1215, Reactome:RELATED-TO:REACT_32396, Reactome:RELATED-TO:REACT_55273, Reactome:RELATED-TO:REACT_79844, Reactome:RELATED-TO:REACT_83849, Reactome:RELATED-TO:REACT_85754, Reactome:RELATED-TO:REACT_96683, Reactome:RELATED-TO:REACT_97368, Reactome:RELATED-TO:REACT_99910, Reactome:RELATED-TO:REACT_103252


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Thu Apr 28, 2016, biocyc14.